Synthesis of Functionalized α‐Vinyl Aldehydes from Enaminones

An efficient RhII‐catalyzed synthesis of functionalized α‐vinyl aldehydes with high E/Z stereoselectivity was developed. The reaction mediates the cyclopropanation of enaminones with vinyl carbenoids that are generated from cyclopropenes in situ to give the aminocyclopropane intermediates. Selective...

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Veröffentlicht in:	Angewandte Chemie International Edition 2019-09, Vol.58 (36), p.12674-12679
Hauptverfasser:	Chen, Jie, Guo, Pan, Zhang, Jianguo, Rong, Jiaxin, Sun, Wangbin, Jiang, Yaojia, Loh, Teck‐Peng
Format:	Artikel
Sprache:	eng
Schlagworte:	Aldehydes carbene chemistry Chemical synthesis Cyclopropane enaminones Intermediates Organic compounds ruthenium Selectivity Stereoselectivity Substrates synthetic methods α-vinyl aldehydes
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