Synthetic Disaccharide Standards Enable Quantitative Analysis of Stored Heparan Sulfate in MPS IIIA Murine Brain Regions

Heparan sulfate (HS) is a complex polysaccharide from the glycosaminoglycan (GAG) family that accumulates in tissues in several neurological lysosomal storage diseases known as mucopolysaccharidosis (MPS) disorders. The quantitation of HS in biological samples is important for studying MPS disorders...

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Veröffentlicht in:	ACS chemical neuroscience 2019-08, Vol.10 (8), p.3847-3858
Hauptverfasser:	He, Qi Qi, Trim, Paul J, Lau, Adeline A, King, Barbara M, Hopwood, John J, Hemsley, Kim M, Snel, Marten F, Ferro, Vito
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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