A facile one pot synthesis of novel pyrimidine derivatives of 1,5-benzodiazepines via domino reaction and their antibacterial evaluation

A new series of pyrimidine (8, 14, 18 and 23) embellished analogues of 1,5-benzodiazepines were synthesized by the one-pot domino approach using the catalyst DABCO (1,4-diazabicyclo[2.2.2]octane). For each compound synthesized, anti-microbial efficacy was determined using broth microdilution assay a...

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Veröffentlicht in:	Journal of microbiological methods 2019-08, Vol.163, p.105648-105648, Article 105648
Hauptverfasser:	Misra, Apoorva, Jain, Sonika, Kishore, Dharma, Dave, Vivek, Reddy, Kakarla Raghava, Sadhu, Veera, Dwivedi, Jaya, Sharma, Swapnil
Format:	Artikel
Sprache:	eng
Schlagworte:	1,5-benzodiazepine Antibacterial activity Bacteria Domino approach Pyrimidine compounds
Online-Zugang:	Volltext
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