A multilayered sheet-type device capable of sustained drug release and deployment control

Minimally invasive delivery of a sustained drug release device to the body is a promising approach for treating chronic conditions such as retinal diseases. Herein, we describe a sheet-type device capable of sustained drug release and deployment control after being applied to the body through a smal...

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Veröffentlicht in:	Biomedical microdevices 2019-09, Vol.21 (3), p.60-8, Article 60
Hauptverfasser:	Sato, Yuto, Nagai, Nobuhiro, Abe, Toshiaki, Kaji, Hirokazu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and Medical Physics Biomedical Engineering and Bioengineering Biophysics Chronic conditions Chronic illnesses Controlled release Curvature Delayed-Action Preparations Drug delivery systems Drug Delivery Systems - instrumentation Engineering Engineering Fluid Dynamics Epithelium Eye - metabolism Fluorescein Fluorescein - metabolism Fluorescence Implantation Injectors Male Nanotechnology Organs Polyethylene glycol Rabbits Retina Retinal pigment epithelium Side effects Transplantation Triethylene glycol dimethacrylate
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