Pyroptosis engagement and bladder urothelial cell-derived exosomes recruit mast cells and induce barrier dysfunction of bladder urothelium after uropathogenic E. coli infection

The specific regulatory mechanism of bladder urothelial barrier dysfunction after infection with uropathogenic (UPEC) is still unclear. The cross talk between bladder urothelial cells and mast cells may play an important role during UPEC infection. In this study, the pyroptosis of urothelial cells w...

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Veröffentlicht in:American Journal of Physiology: Cell Physiology 2019-09, Vol.317 (3), p.C544-C555
Hauptverfasser: Wu, Zonglong, Li, Yan, Liu, Qinggang, Liu, Yaxiao, Chen, Lipeng, Zhao, Hongda, Guo, Hongda, Zhu, Kejia, Zhou, Nan, Chai, Toby C, Shi, Benkang
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Sprache:eng
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