Methods comparison biases due to differing uncertainties and data censoring

Background Measurements on clinical specimens that contain no analyte, or very low amounts of analyte, unavoidably generate assay response (signal) measurements that fall on the ‘negative’ side of the fitted zero response. It is virtually universal practice to left-censor such measurements to zero a...

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Bibliographische Detailangaben

Veröffentlicht in:	Annals of clinical biochemistry 2019-09, Vol.56 (5), p.608-612
1. Verfasser:	Sadler, William A
Format:	Artikel
Sprache:	eng
Schlagworte:	Bias Humans Limit of Detection Models, Statistical Uncertainty
Online-Zugang:	Volltext
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