Management of immune-related adverse events in endocrine organs induced by immune checkpoint inhibitors: clinical guidelines of the Japan Endocrine Society

Immune checkpoint inhibitors (ICIs) have become a promising treatment for advanced malignancies. However, these drugs can induce immune-related adverse events (irAEs) in several organs, including skin, gastrointestinal tract, liver, muscle, nerve, and endocrine organs. Endocrine irAEs comprise hypop...

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Veröffentlicht in:	Endocrine Journal 2019, Vol.66(7), pp.581-586
Hauptverfasser:	Arima, Hiroshi, Iwama, Shintaro, Inaba, Hidefumi, Ariyasu, Hiroyuki, Makita, Noriko, Otsuki, Michio, Kageyama, Kazunori, Imagawa, Akihisa, Akamizu, Takashi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal Gland Diseases - chemically induced Adrenal Gland Diseases - therapy Adrenal glands Adrenal insufficiency Antibodies, Monoclonal - adverse effects Antibodies, Monoclonal - therapeutic use Cell Cycle Checkpoints - drug effects Cell Cycle Checkpoints - immunology Diabetes Diabetes mellitus Diabetes mellitus (insulin dependent) Diabetes Mellitus - chemically induced Diabetes Mellitus - immunology Diabetes Mellitus - therapy Endocrine System Diseases - chemically induced Endocrine System Diseases - diagnosis Endocrine System Diseases - therapy Gastrointestinal tract Humans Hypocalcemia Hypoparathyroidism Hypopituitarism Immune checkpoint inhibitors Immune System Diseases - chemically induced Immune System Diseases - diagnosis Immune System Diseases - therapy Immunologic Factors - adverse effects Immunologic Factors - therapeutic use Immunosuppressive agents Japan Ketoacidosis Parathyroid Diseases - chemically induced Parathyroid Diseases - therapy Protein Kinase Inhibitors - adverse effects Protein Kinase Inhibitors - therapeutic use Skin Societies, Medical - organization & administration Societies, Medical - standards Thyroid Thyroid diseases Thyroid Diseases - chemically induced Thyroid Diseases - therapy Thyroid dysfunction Thyroid gland
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