Immunogenicity of Intramuscular Fractional Dose of Inactivated Poliovirus Vaccine

Abstract Backgrounds Intradermal (id) fractional inactivated poliovirus vaccine ([fIPV] one fifth of normal IPV dose) is safe and immunogenic; however, id administration is perceived as difficult. We compared fIPV immunogenicity administered id or intramuscularly (im). Methods This noninferiority tr...

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Veröffentlicht in:	The Journal of infectious diseases 2020-03, Vol.221 (6), p.895-901
Hauptverfasser:	Resik, Sonia, Mach, Ondrej, Tejeda, Alina, Jeyaseelan, Visalakshi, Fonseca, Magile, Diaz, Manuel, Alemany, Nilda, Hung, Lai Heng, Aleman, Yoan, Mesa, Ileana, Garcia, Gloria, Sutter, Roland W
Format:	Artikel
Sprache:	eng
Schlagworte:	Dose-Response Relationship, Immunologic Female Humans Immunization Immunogenicity Immunogenicity, Vaccine Infant Infants Injections, Intradermal Injections, Intramuscular Male Poliovirus Vaccine, Inactivated - administration & dosage Poliovirus Vaccine, Inactivated - immunology Seroconversion Serotypes Vaccines
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