Multifunctional transcriptional coactivator PC4 is a global co-regulator of p53-dependent stress response and gene regulation

Abstract Human positive coactivator 4 (PC4), a multifunctional chromatin-associated protein, is known to directly interact with p53 and modulate expressions of a few p53-dependent genes. However, the role of PC4 in p53's myriad of other regulatory functions is not known. The p53–PC4 interaction...

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Veröffentlicht in:	Journal of biochemistry (Tokyo) 2019-11, Vol.166 (5), p.403-413
Hauptverfasser:	Mondal, Priya, Saleem, Suraiya, Sikder, Sweta, Kundu, Tapas K, Biswas, Subhas Chandra, Roy, Siddhartha
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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