Role of microRNAs in glucocorticoid‑resistant B‑cell precursor acute lymphoblastic leukemia

Acute lymphoblastic leukemia (ALL) is the most common malignant disorder in children and intensive combination therapy has markedly improved patient prognosis. However, efficacy of the treatment still fails in 10‑15% of patients. Glucocorticoids (GCs) such as prednisone and dexamethasone (DEX) are e...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Oncology reports 2019-08, Vol.42 (2), p.708-716
Hauptverfasser:	Sakurai, Naoto, Komada, Yoshihiro, Hanaki, Ryo, Morimoto, Mari, Ito, Takahiro, Nakato, Daisuke, Hirayama, Masahiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute lymphocytic leukemia Analysis Apoptosis Biochemistry Biomarkers, Tumor - genetics Biotechnology industries Cancer treatment Cell death Cell growth Cell Proliferation Chemotherapy Deoxyribonucleic acid Dexamethasone DNA Drug Resistance, Neoplasm - genetics Gene Expression Regulation, Neoplastic - drug effects Glucocorticoids Glucocorticoids - pharmacology Humans Leukemia Lymphocytic leukemia Medical prognosis Medical research MicroRNA MicroRNAs MicroRNAs - genetics Pediatrics Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - drug therapy Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - genetics Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - pathology Prednisone Prognosis Protein expression Proteins Scientific equipment industry Signal Transduction Tumor Cells, Cultured
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!