A triple-amplification strategy based on the formation of peroxidase-like two-dimensional DNA/Fe3O4 networks initiated by the hybridization chain reaction for highly sensitive detection of microRNA

A highly sensitive triple-amplification assay for the detection of microRNA (miRNA) let-7a is reported in this work. The assay relies on the formation of magnetic two-dimensional DNA/Fe3O4 nanosheet networks initiated by the target miRNA-associated hybridization chain reaction. The Fe3O4 nanosheets...

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Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2019-07, Vol.55 (58), p.8386-8389
Hauptverfasser:	Tang, Sheng, Li, Yana, Zhu, Anni, Yao, Yao, Sun, Jun, Zheng, Fenfen, Lin, Zixia, Shen, Wei
Format:	Artikel
Sprache:	eng
Schlagworte:	Amplification Assaying Catalysis Catalytic activity Colorimetry Deoxyribonucleic acid DNA Iron oxides MicroRNAs Nanosheets Networks Peroxidase Ribonucleic acid RNA Signal to noise ratio
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