Role of melanoma inhibitory activity in melanocyte senescence

The protein melanoma inhibitory activity (MIA) is known to be expressed in melanoma and to support melanoma progression. Interestingly, previous studies also observed the expression of MIA in nevi. Concentrating on these findings, we revealed that MIA expression is correlated with a senescent state...

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Veröffentlicht in:	Pigment cell and melanoma research 2019-11, Vol.32 (6), p.777-791
Hauptverfasser:	Feuerer, Lena, Lamm, Susanne, Henz, Ingmar, Kappelmann‐Fenzl, Melanie, Haferkamp, Sebastian, Meierjohann, Svenja, Hellerbrand, Claus, Kuphal, Silke, Bosserhoff, Anja Katrin
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell cycle Cell proliferation Cyclin-dependent kinase inhibitor p21 melanocyte Melanocytes Melanoma melanoma inhibitory activity oncogene‐induced senescence p21 Rodents Senescence telomerase Telomerase reverse transcriptase
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