The MELAS mutation m.3243A>G alters the expression of mitochondrial tRNA fragments

Recent evidences highlight the importance of mitochondria-nucleus communication for the clinical phenotype of oxidative phosphorylation (OXPHOS) diseases. However, the participation of small non-coding RNAs (sncRNAs) in this communication has been poorly explored. We asked whether OXPHOS dysfunction...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biochimica et biophysica acta. Molecular cell research 2019-09, Vol.1866 (9), p.1433-1449
Hauptverfasser:	Meseguer, Salvador, Navarro-González, Carmen, Panadero, Joaquin, Villarroya, Magda, Boutoual, Rachid, Sánchez-Alcázar, Jose Antonio, Armengod, M.-Eugenia
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Nucleus - genetics Cell Nucleus - metabolism Down-Regulation Gene Expression Regulation GTP-Binding Proteins GTPBP3/MTO1/TRMU HeLa Cells Humans MELAS Syndrome - genetics MELAS Syndrome - metabolism MicroRNAs - genetics miRNAs Mitochondria - genetics Mitochondria - metabolism Mitochondrial dysfunction Mitochondrial Membrane Transport Proteins - genetics Mitochondrial Proteins Mitochondrial-tRNA modification Monocarboxylic Acid Transporters - genetics Mutation Oxidative Phosphorylation Retrograde signaling RNA, Small Untranslated RNA, Transfer, Leu - genetics RNA-Binding Proteins Signal Transduction sncRNAs Transcriptome tRNA Methyltransferases
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!