Impact of diet on the persistence of early vascular remodeling and stiffening induced by intrauterine growth restriction and a maternal high-fat diet

Intrauterine growth restriction (IUGR) and maternal high-fat diet (HFD) independently predispose offspring to hypertension. In a rat model, IUGR more so than maternal HFD increases arterial stiffness with vascular remodeling as early as (PND) . The trajectory of such early vascular changes remains u...

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Veröffentlicht in:American journal of physiology. Heart and circulatory physiology 2019-08, Vol.317 (2), p.H424-H433
Hauptverfasser: Miller, Thomas A, Dodson, R Blair, Mankouski, Anastasiya, Powers, Kyle N, Yang, Yueqin, Yu, Baifeng, Zinkhan, Erin K
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Sprache:eng
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