In vivo effect of bevacizumab-loaded albumin nanoparticles in the treatment of corneal neovascularization

Corneal neovascularization (CNV) is associated with different ocular pathologies, including infectious keratitis, trachoma or corneal trauma. Pharmacological treatments based on the topical application of anti-VEGF therapies have been shown to be effective in the treatment and prevention of CNV. The...

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Veröffentlicht in:	Experimental eye research 2019-08, Vol.185, p.107697-107697, Article 107697
Hauptverfasser:	Luis de Redín, Inés, Boiero, Carolina, Recalde, Sergio, Agüeros, Maite, Allemandi, Daniel, Llabot, Juan M., García-Layana, Alfredo, Irache, Juan M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Inhibitors - therapeutic use Animals Bevacizumab Bevacizumab - therapeutic use Coated Materials, Biocompatible Corneal neovascularization Corneal Neovascularization - drug therapy Corneal Neovascularization - pathology Disease Models, Animal Drug Carriers - chemistry Human serum albumin Male Nanoparticles Nanoparticles - chemistry Ocular delivery Pegylated Polyethylene Glycols Rats Rats, Wistar Serum Albumin, Human - chemistry Vascular Endothelial Growth Factor A - antagonists & inhibitors
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