Diaphragm‐based optical fiber sensor for pulse wave monitoring and cardiovascular diseases diagnosis

Arterial pulse wave has been considered as a vital sign in assessment of cardiovascular diseases. Noninvasive pulse sensor with compact structure, immunity to electro‐magnetic interference and high sensitivity is the research focus in recent years. While, optical fiber biosensor is a competitive opt...

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Veröffentlicht in:Journal of biophotonics 2019-10, Vol.12 (10), p.e201900084-n/a
Hauptverfasser: Wang, Jingyi, Liu, Kewei, Sun, Qizhen, Ni, Xiaoling, Ai, Fan, Wang, Senmao, Yan, Zhijun, Liu, Deming
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container_issue 10
container_start_page e201900084
container_title Journal of biophotonics
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creator Wang, Jingyi
Liu, Kewei
Sun, Qizhen
Ni, Xiaoling
Ai, Fan
Wang, Senmao
Yan, Zhijun
Liu, Deming
description Arterial pulse wave has been considered as a vital sign in assessment of cardiovascular diseases. Noninvasive pulse sensor with compact structure, immunity to electro‐magnetic interference and high sensitivity is the research focus in recent years. While, optical fiber biosensor is a competitive option to meet these needs. Here, a diaphragm‐based optical fiber pulse sensor was proposed to achieve high‐precision radial pulse wave monitoring. A wearable device was developed, composed of a sports wristband and an aluminum diaphragm‐based optical fiber sensor tip of only 1 cm in diameter, which was highly sensitive to the weak acoustic signal. In particular, coherent phase detection was adopted to improve detection signal‐to‐noise ratio, so as to recover the high‐fidelity pulse waveforms. A clinical experiment was carried out to detect and morphological analyze the pulse waveforms of four subjects, the results of which preliminarily demonstrated the feasibility of pulse diagnosis method. The proposed pulse fiber sensor provides a comfortable way for pulse diagnosis, which is promising in early cardiovascular diseases indicating. Arterial pulse wave has been considered as a vital sign in assessment of cardiovascular diseases. Optical fiber biosensor has competitive characteristics of compactness, immunity to electro‐magnetic interference and high sensitivity. Here, a diaphragm based optical fiber pulse sensor is proposed and made into wearable device to achieve high‐precision radial pulse wave monitoring, which provides a comfortable way for pulse diagnosis, promising in early cardiovascular diseases indicating.
doi_str_mv 10.1002/jbio.201900084
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Noninvasive pulse sensor with compact structure, immunity to electro‐magnetic interference and high sensitivity is the research focus in recent years. While, optical fiber biosensor is a competitive option to meet these needs. Here, a diaphragm‐based optical fiber pulse sensor was proposed to achieve high‐precision radial pulse wave monitoring. A wearable device was developed, composed of a sports wristband and an aluminum diaphragm‐based optical fiber sensor tip of only 1 cm in diameter, which was highly sensitive to the weak acoustic signal. In particular, coherent phase detection was adopted to improve detection signal‐to‐noise ratio, so as to recover the high‐fidelity pulse waveforms. A clinical experiment was carried out to detect and morphological analyze the pulse waveforms of four subjects, the results of which preliminarily demonstrated the feasibility of pulse diagnosis method. The proposed pulse fiber sensor provides a comfortable way for pulse diagnosis, which is promising in early cardiovascular diseases indicating. Arterial pulse wave has been considered as a vital sign in assessment of cardiovascular diseases. Optical fiber biosensor has competitive characteristics of compactness, immunity to electro‐magnetic interference and high sensitivity. Here, a diaphragm based optical fiber pulse sensor is proposed and made into wearable device to achieve high‐precision radial pulse wave monitoring, which provides a comfortable way for pulse diagnosis, promising in early cardiovascular diseases indicating.</description><identifier>ISSN: 1864-063X</identifier><identifier>EISSN: 1864-0648</identifier><identifier>DOI: 10.1002/jbio.201900084</identifier><identifier>PMID: 31219245</identifier><language>eng</language><publisher>Weinheim: WILEY‐VCH Verlag GmbH &amp; Co. 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Noninvasive pulse sensor with compact structure, immunity to electro‐magnetic interference and high sensitivity is the research focus in recent years. While, optical fiber biosensor is a competitive option to meet these needs. Here, a diaphragm‐based optical fiber pulse sensor was proposed to achieve high‐precision radial pulse wave monitoring. A wearable device was developed, composed of a sports wristband and an aluminum diaphragm‐based optical fiber sensor tip of only 1 cm in diameter, which was highly sensitive to the weak acoustic signal. In particular, coherent phase detection was adopted to improve detection signal‐to‐noise ratio, so as to recover the high‐fidelity pulse waveforms. A clinical experiment was carried out to detect and morphological analyze the pulse waveforms of four subjects, the results of which preliminarily demonstrated the feasibility of pulse diagnosis method. The proposed pulse fiber sensor provides a comfortable way for pulse diagnosis, which is promising in early cardiovascular diseases indicating. Arterial pulse wave has been considered as a vital sign in assessment of cardiovascular diseases. Optical fiber biosensor has competitive characteristics of compactness, immunity to electro‐magnetic interference and high sensitivity. 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source Wiley Journals
subjects Acoustic noise
Aluminum
biomedical sensor
Biosensors
Cardiovascular diseases
Diagnosis
diaphragm
Monitoring
non‐invasive measurement
optical fiber sensor
Optical fibers
pulse wave diagnosis
Sensors
Waveforms
Wearable technology
title Diaphragm‐based optical fiber sensor for pulse wave monitoring and cardiovascular diseases diagnosis
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