Enhanced PDGF signaling in gestational diabetes mellitus is involved in pancreatic β-cell dysfunction

Gestational diabetes mellitus (GDM) is often accompanied by the development of hyperinsulinemia as an adaptation to increased insulin demand, but this subsequently causes insulin resistance. Loss of function in pancreatic β-cells further aggravates the development of GDM. The level of serum platelet...

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Veröffentlicht in:	Biochemical and biophysical research communications 2019-08, Vol.516 (2), p.402-407
Hauptverfasser:	Shan, Zhenli, Xu, Chuanlu, Wang, Wangsheng, Li, Wenjiao
Format:	Artikel
Sprache:	eng
Schlagworte:	Dedifferentiation Gestational diabetes mellitus Pancreatic β-cell dysfunction Platelet-derived growth factor
Online-Zugang:	Volltext
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