Combination of pentoxifylline and α-galactosylceramide with radiotherapy promotes necro-apoptosis and leukocyte infiltration and reduces the mitosis rate in murine melanoma

[Display omitted] •PTX is a potent inductor of necro-apoptosis.•α-galactosilceramide (αGalCer) prevents the growth of tumor volume.•PTX and αGalCer have an additive effect over tumor volume diminution.•Radiotherapy plus PTX+αGalCer induce leukocyte infiltration in solid melanoma and increase necro-a...

Ausführliche Beschreibung