Gold nanoparticles regulate tight junctions and improve cetuximab effect in colon cancer cells

Colon cancer (CC) is the second cause of cancer death worldwide. The use of nanoparticles for drug delivery has been increasing in cancer clinical trials over recent years. We evaluated cytotoxicity of citrate-capped gold nanoparticles (GNPs) and the role they play on cell–cell adhesion. We also use...

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Veröffentlicht in:	Nanomedicine (London, England) England), 2019-06, Vol.14 (12), p.1565-1578
Hauptverfasser:	Leve, Fernanda, Bonfim, Daniella P, Fontes, Giselle, Morgado-Díaz, José A
Format:	Artikel
Sprache:	eng
Schlagworte:	Autophagy Cancer therapies Cell adhesion & migration cell–cell adhesion cetuximab colon cancer Colorectal cancer Cytotoxicity Drug delivery systems EGFR gold nanoparticle Immunoglobulins Immunotherapy Investigations Lung cancer Monoclonal antibodies Mutation Nanoparticles Permeability Physiology Proteins Regulatory approval Targeted cancer therapy tight junction Tumors
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