Design, synthesis and anticervical cancer activity of new benzofuran–pyrazol-hydrazono- thiazolidin-4-one hybrids as potential EGFR inhibitors and apoptosis inducing agents

[Display omitted] •A new set of 2-(((3-(benzofuran-2-yl)-1-phenyl-1H-pyrazol-4-yl)methylene)hydrazono)-5-(aryl)thiazolidin-4-one derivatives were designed and synthesized.•In vitro cytotoxic evaluation was carried out against human cervix carcinoma (Hela) cells and the most active derivatives were e...

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Veröffentlicht in:	Bioorganic chemistry 2019-08, Vol.89, p.103035-103035, Article 103035
Hauptverfasser:	Abbas, Hebat-Allah S., Abd El-Karim, Somaia S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis and EGFR PK suppressing agents Benzofuran Cervical cancer Pyrazole Thiazolidin-4-one
Online-Zugang:	Volltext
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