Serum Concentrations of Oocyte-Secreted Factors BMP15 and GDF9 During IVF and in Women With Reproductive Pathologies

Abstract Oocyte-secreted factors bone morphogenetic protein 15 (BMP15) and growth differentiation factor 9 (GDF9) are critical for folliculogenesis and fertility. This study developed ELISAs for the measurement of BMP15 and GDF9 in serum and investigated their usefulness as biomarkers of female repr...

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Veröffentlicht in:	Endocrinology (Philadelphia) 2019-10, Vol.160 (10), p.2298-2313
Hauptverfasser:	Riepsamen, Angelique H, Chan, Karen, Lien, Shelly, Sweeten, Prudence, Donoghoe, Mark W, Walker, Glenda, Fraison, Eloïse H J, Stocker, William A, Walton, Kelly L, Harrison, Craig A, Ledger, William L, Robertson, David M, Gilchrist, Robert B
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Analysis Biological markers Biomarkers Bone morphogenetic proteins Diagnosis Diagnostic systems Endocrinology Fertility Folliculogenesis Gametocytes Genital diseases, Female Gonadotropins Growth differentiation factor 9 Growth factors Health aspects Immunoassay Immunoassays In vitro fertilization Infertility Measurement Oocytes Ovulation Pituitary (anterior) Polycystic ovary syndrome Post-menopause Sensitivity
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