RANKL blockade suppresses pathological angiogenesis and vascular leakage in ischemic retinopathy

Receptor activator of NF-κB ligand (RANKL) is a member of the TNF superfamily. RANKL increases endothelial permeability and induces angiogenesis, suggesting its critical roles in the vasculature. Despite the evidence implicating RANKL in vascular pathology, its role in ischemic retinopathy has not b...

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Veröffentlicht in:	Biochemical and biophysical research communications 2019-08, Vol.516 (2), p.350-356
Hauptverfasser:	Ock, Sangmi, Park, Soyoung, Lee, Junyeop, Kim, Jaetaek
Format:	Artikel
Sprache:	eng
Schlagworte:	Neovascularization Pericyte Permeability Receptor activator of NF-κB ligand Retina
Online-Zugang:	Volltext
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