Sphingolipids and the unfolded protein response

The unfolded protein response (UPR) is a response by the endoplasmic reticulum to stress, classically caused by any disruption to cell homeostasis that results in an accumulation in unfolded proteins. However, there is an increasing body of research demonstrating that the UPR can also be activated b...

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Veröffentlicht in:	Biochimica et biophysica acta. Molecular and cell biology of lipids 2019-10, Vol.1864 (10), p.1483-1494
Hauptverfasser:	Bennett, Melissa K., Wallington-Beddoe, Craig T., Pitson, Stuart M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Cell Proliferation Ceramide Diabetes Mellitus - metabolism Endoplasmic reticulum stress Humans Liver Diseases - metabolism Neoplasms - metabolism Sphingolipids Sphingolipids - metabolism Unfolded Protein Response
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