Risk of Malignancy in FDG-Avid Thyroid Incidentalomas on PET/CT: A Prospective Study
Background Due to a substantial risk of malignancy, patients with focal FDG-avid thyroid incidentalomas (FFTIs) on PET/CT are in most of Denmark referred to Head and Neck Cancer (HNC) fast track programs. The aim of this study was to determine the risk of malignancy in FFTI managed in a HNC fast tra...
Gespeichert in:
| Veröffentlicht in: | World journal of surgery 2019-10, Vol.43 (10), p.2454-2458 |
|---|---|
| Hauptverfasser: | , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 2458 |
|---|---|
| container_issue | 10 |
| container_start_page | 2454 |
| container_title | World journal of surgery |
| container_volume | 43 |
| creator | Abdel-Halim, Chadi Nimeh Rosenberg, Tine Bjørndal, Kristine Madsen, Anders Rørbæk Jakobsen, John Døssing, Helle Bay, Mette Thomassen, Anders Nielsen, Anne Lerberg Godballe, Christian |
| description | Background
Due to a substantial risk of malignancy, patients with focal FDG-avid thyroid incidentalomas (FFTIs) on PET/CT are in most of Denmark referred to Head and Neck Cancer (HNC) fast track programs. The aim of this study was to determine the risk of malignancy in FFTI managed in a HNC fast track program.
Methods
A prospective cohort study including all patients with FFTI referred to the HNC fast track program, Odense University Hospital between September 1, 2016 and August 31, 2017. Ultrasonography (US) and fine-needle aspiration biopsy (FNAB) were intended to be done in all patients. Nodules with cytology of Bethesda 1, 3, 4, 5, or 6 were planned for surgical removal
.
Results
A total of 104 patients were included. All patients had US and 101 patients (97%) had FNAB. Forty-two patients had benign cytology classified as Bethesda 2. The remaining 62 patients underwent surgery except from 11 patients, mainly due to comorbidity. The overall risk of malignancy for patients with FFTI referred to our HNC fast track program was calculated to be 24% (23/95) based on patients with unequivocal cytology and/or histology. The only statistically significant US characteristic to predict malignancy was the appearance of irregular margins with a sensitivity of 47% and specificity of 96%.
Conclusion
The risk of malignancy of FFTIs handled in our HNC fast track program is 24%. |
| doi_str_mv | 10.1007/s00268-019-05043-6 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2235063149</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2235063149</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4704-86cc57daf3b68810dbe5f0ee6013d15241d829be3e7f5c15ec60d2be457060aa3</originalsourceid><addsrcrecordid>eNqNkE1v1DAURS0EokPLH2CBLLFhE_r8mUx306FTiopatUEsLcd5KS4ZZ4gnrfLv6yEFJBaoq-fFOVfXl5A3DD4wgPwwAnBdZMDmGSiQItPPyIxJwTMuuHhOZiC0TG8m9sirGG8BWK5BvyR7gjHNhJIzUl75-IN2Df1iW38TbHAj9YGuPp5miztf0_L72HfpngXnawxb23ZrG2kX6OVJebgsj-iCXvZd3KDb-juk19uhHg_Ii8a2EV8_3n3ydXVSLj9l5xenZ8vFeeZkDjIrtHMqr20jKl0UDOoKVQOIGpiomeKS1QWfVygwb5RjCp2GmlcoVQ4arBX75P2Uu-m7nwPGrVn76LBtbcBuiIZzoUALJucJffcPetsNfUjtdpTkRV6wPFF8olz6UuyxMZver20_GgZmt7mZNjdpc_Nrc6OT9PYxeqjWWP9Rfo-cgKMJuPctjk-INN8-Xx-vAEDvZDHJMXnhBvu_xf_T6QE55ZqS</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2234287817</pqid></control><display><type>article</type><title>Risk of Malignancy in FDG-Avid Thyroid Incidentalomas on PET/CT: A Prospective Study</title><source>MEDLINE</source><source>SpringerNature Journals</source><source>Access via Wiley Online Library</source><creator>Abdel-Halim, Chadi Nimeh ; Rosenberg, Tine ; Bjørndal, Kristine ; Madsen, Anders Rørbæk ; Jakobsen, John ; Døssing, Helle ; Bay, Mette ; Thomassen, Anders ; Nielsen, Anne Lerberg ; Godballe, Christian</creator><creatorcontrib>Abdel-Halim, Chadi Nimeh ; Rosenberg, Tine ; Bjørndal, Kristine ; Madsen, Anders Rørbæk ; Jakobsen, John ; Døssing, Helle ; Bay, Mette ; Thomassen, Anders ; Nielsen, Anne Lerberg ; Godballe, Christian</creatorcontrib><description>Background
Due to a substantial risk of malignancy, patients with focal FDG-avid thyroid incidentalomas (FFTIs) on PET/CT are in most of Denmark referred to Head and Neck Cancer (HNC) fast track programs. The aim of this study was to determine the risk of malignancy in FFTI managed in a HNC fast track program.
Methods
A prospective cohort study including all patients with FFTI referred to the HNC fast track program, Odense University Hospital between September 1, 2016 and August 31, 2017. Ultrasonography (US) and fine-needle aspiration biopsy (FNAB) were intended to be done in all patients. Nodules with cytology of Bethesda 1, 3, 4, 5, or 6 were planned for surgical removal
.
Results
A total of 104 patients were included. All patients had US and 101 patients (97%) had FNAB. Forty-two patients had benign cytology classified as Bethesda 2. The remaining 62 patients underwent surgery except from 11 patients, mainly due to comorbidity. The overall risk of malignancy for patients with FFTI referred to our HNC fast track program was calculated to be 24% (23/95) based on patients with unequivocal cytology and/or histology. The only statistically significant US characteristic to predict malignancy was the appearance of irregular margins with a sensitivity of 47% and specificity of 96%.
Conclusion
The risk of malignancy of FFTIs handled in our HNC fast track program is 24%.</description><identifier>ISSN: 0364-2313</identifier><identifier>EISSN: 1432-2323</identifier><identifier>DOI: 10.1007/s00268-019-05043-6</identifier><identifier>PMID: 31161354</identifier><language>eng</language><publisher>Cham: Springer International Publishing</publisher><subject>Abdominal Surgery ; Adult ; Aged ; Aged, 80 and over ; Algorithms ; Biopsy ; Biopsy, Fine-Needle ; Cardiac Surgery ; Cellular biology ; Cytology ; Denmark ; Female ; Fluorodeoxyglucose F18 - metabolism ; General Surgery ; Head & neck cancer ; Health risk assessment ; Histology ; Humans ; Incidental Findings ; Male ; Malignancy ; Medicine ; Medicine & Public Health ; Middle Aged ; Nodules ; Original Scientific Report ; Patients ; Positron Emission Tomography Computed Tomography ; Prospective Studies ; Risk ; Risk management ; Sensitivity and Specificity ; Statistical analysis ; Surgery ; Thoracic Surgery ; Thyroid ; Thyroid gland ; Thyroid Neoplasms - diagnostic imaging ; Thyroid Neoplasms - pathology ; Thyroid Nodule - diagnostic imaging ; Thyroid Nodule - pathology ; Ultrasonography ; Ultrasound ; Vascular Surgery</subject><ispartof>World journal of surgery, 2019-10, Vol.43 (10), p.2454-2458</ispartof><rights>Société Internationale de Chirurgie 2019</rights><rights>2019 The Author(s) under exclusive licence to Société Internationale de Chirurgie</rights><rights>World Journal of Surgery is a copyright of Springer, (2019). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4704-86cc57daf3b68810dbe5f0ee6013d15241d829be3e7f5c15ec60d2be457060aa3</citedby><cites>FETCH-LOGICAL-c4704-86cc57daf3b68810dbe5f0ee6013d15241d829be3e7f5c15ec60d2be457060aa3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00268-019-05043-6$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00268-019-05043-6$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>315,782,786,1419,27933,27934,41497,42566,45583,45584,51328</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31161354$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Abdel-Halim, Chadi Nimeh</creatorcontrib><creatorcontrib>Rosenberg, Tine</creatorcontrib><creatorcontrib>Bjørndal, Kristine</creatorcontrib><creatorcontrib>Madsen, Anders Rørbæk</creatorcontrib><creatorcontrib>Jakobsen, John</creatorcontrib><creatorcontrib>Døssing, Helle</creatorcontrib><creatorcontrib>Bay, Mette</creatorcontrib><creatorcontrib>Thomassen, Anders</creatorcontrib><creatorcontrib>Nielsen, Anne Lerberg</creatorcontrib><creatorcontrib>Godballe, Christian</creatorcontrib><title>Risk of Malignancy in FDG-Avid Thyroid Incidentalomas on PET/CT: A Prospective Study</title><title>World journal of surgery</title><addtitle>World J Surg</addtitle><addtitle>World J Surg</addtitle><description>Background
Due to a substantial risk of malignancy, patients with focal FDG-avid thyroid incidentalomas (FFTIs) on PET/CT are in most of Denmark referred to Head and Neck Cancer (HNC) fast track programs. The aim of this study was to determine the risk of malignancy in FFTI managed in a HNC fast track program.
Methods
A prospective cohort study including all patients with FFTI referred to the HNC fast track program, Odense University Hospital between September 1, 2016 and August 31, 2017. Ultrasonography (US) and fine-needle aspiration biopsy (FNAB) were intended to be done in all patients. Nodules with cytology of Bethesda 1, 3, 4, 5, or 6 were planned for surgical removal
.
Results
A total of 104 patients were included. All patients had US and 101 patients (97%) had FNAB. Forty-two patients had benign cytology classified as Bethesda 2. The remaining 62 patients underwent surgery except from 11 patients, mainly due to comorbidity. The overall risk of malignancy for patients with FFTI referred to our HNC fast track program was calculated to be 24% (23/95) based on patients with unequivocal cytology and/or histology. The only statistically significant US characteristic to predict malignancy was the appearance of irregular margins with a sensitivity of 47% and specificity of 96%.
Conclusion
The risk of malignancy of FFTIs handled in our HNC fast track program is 24%.</description><subject>Abdominal Surgery</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Algorithms</subject><subject>Biopsy</subject><subject>Biopsy, Fine-Needle</subject><subject>Cardiac Surgery</subject><subject>Cellular biology</subject><subject>Cytology</subject><subject>Denmark</subject><subject>Female</subject><subject>Fluorodeoxyglucose F18 - metabolism</subject><subject>General Surgery</subject><subject>Head & neck cancer</subject><subject>Health risk assessment</subject><subject>Histology</subject><subject>Humans</subject><subject>Incidental Findings</subject><subject>Male</subject><subject>Malignancy</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Nodules</subject><subject>Original Scientific Report</subject><subject>Patients</subject><subject>Positron Emission Tomography Computed Tomography</subject><subject>Prospective Studies</subject><subject>Risk</subject><subject>Risk management</subject><subject>Sensitivity and Specificity</subject><subject>Statistical analysis</subject><subject>Surgery</subject><subject>Thoracic Surgery</subject><subject>Thyroid</subject><subject>Thyroid gland</subject><subject>Thyroid Neoplasms - diagnostic imaging</subject><subject>Thyroid Neoplasms - pathology</subject><subject>Thyroid Nodule - diagnostic imaging</subject><subject>Thyroid Nodule - pathology</subject><subject>Ultrasonography</subject><subject>Ultrasound</subject><subject>Vascular Surgery</subject><issn>0364-2313</issn><issn>1432-2323</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNqNkE1v1DAURS0EokPLH2CBLLFhE_r8mUx306FTiopatUEsLcd5KS4ZZ4gnrfLv6yEFJBaoq-fFOVfXl5A3DD4wgPwwAnBdZMDmGSiQItPPyIxJwTMuuHhOZiC0TG8m9sirGG8BWK5BvyR7gjHNhJIzUl75-IN2Df1iW38TbHAj9YGuPp5miztf0_L72HfpngXnawxb23ZrG2kX6OVJebgsj-iCXvZd3KDb-juk19uhHg_Ii8a2EV8_3n3ydXVSLj9l5xenZ8vFeeZkDjIrtHMqr20jKl0UDOoKVQOIGpiomeKS1QWfVygwb5RjCp2GmlcoVQ4arBX75P2Uu-m7nwPGrVn76LBtbcBuiIZzoUALJucJffcPetsNfUjtdpTkRV6wPFF8olz6UuyxMZver20_GgZmt7mZNjdpc_Nrc6OT9PYxeqjWWP9Rfo-cgKMJuPctjk-INN8-Xx-vAEDvZDHJMXnhBvu_xf_T6QE55ZqS</recordid><startdate>20191015</startdate><enddate>20191015</enddate><creator>Abdel-Halim, Chadi Nimeh</creator><creator>Rosenberg, Tine</creator><creator>Bjørndal, Kristine</creator><creator>Madsen, Anders Rørbæk</creator><creator>Jakobsen, John</creator><creator>Døssing, Helle</creator><creator>Bay, Mette</creator><creator>Thomassen, Anders</creator><creator>Nielsen, Anne Lerberg</creator><creator>Godballe, Christian</creator><general>Springer International Publishing</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QO</scope><scope>7T5</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20191015</creationdate><title>Risk of Malignancy in FDG-Avid Thyroid Incidentalomas on PET/CT: A Prospective Study</title><author>Abdel-Halim, Chadi Nimeh ; Rosenberg, Tine ; Bjørndal, Kristine ; Madsen, Anders Rørbæk ; Jakobsen, John ; Døssing, Helle ; Bay, Mette ; Thomassen, Anders ; Nielsen, Anne Lerberg ; Godballe, Christian</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4704-86cc57daf3b68810dbe5f0ee6013d15241d829be3e7f5c15ec60d2be457060aa3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Abdominal Surgery</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Algorithms</topic><topic>Biopsy</topic><topic>Biopsy, Fine-Needle</topic><topic>Cardiac Surgery</topic><topic>Cellular biology</topic><topic>Cytology</topic><topic>Denmark</topic><topic>Female</topic><topic>Fluorodeoxyglucose F18 - metabolism</topic><topic>General Surgery</topic><topic>Head & neck cancer</topic><topic>Health risk assessment</topic><topic>Histology</topic><topic>Humans</topic><topic>Incidental Findings</topic><topic>Male</topic><topic>Malignancy</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Nodules</topic><topic>Original Scientific Report</topic><topic>Patients</topic><topic>Positron Emission Tomography Computed Tomography</topic><topic>Prospective Studies</topic><topic>Risk</topic><topic>Risk management</topic><topic>Sensitivity and Specificity</topic><topic>Statistical analysis</topic><topic>Surgery</topic><topic>Thoracic Surgery</topic><topic>Thyroid</topic><topic>Thyroid gland</topic><topic>Thyroid Neoplasms - diagnostic imaging</topic><topic>Thyroid Neoplasms - pathology</topic><topic>Thyroid Nodule - diagnostic imaging</topic><topic>Thyroid Nodule - pathology</topic><topic>Ultrasonography</topic><topic>Ultrasound</topic><topic>Vascular Surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Abdel-Halim, Chadi Nimeh</creatorcontrib><creatorcontrib>Rosenberg, Tine</creatorcontrib><creatorcontrib>Bjørndal, Kristine</creatorcontrib><creatorcontrib>Madsen, Anders Rørbæk</creatorcontrib><creatorcontrib>Jakobsen, John</creatorcontrib><creatorcontrib>Døssing, Helle</creatorcontrib><creatorcontrib>Bay, Mette</creatorcontrib><creatorcontrib>Thomassen, Anders</creatorcontrib><creatorcontrib>Nielsen, Anne Lerberg</creatorcontrib><creatorcontrib>Godballe, Christian</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Biotechnology Research Abstracts</collection><collection>Immunology Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>World journal of surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Abdel-Halim, Chadi Nimeh</au><au>Rosenberg, Tine</au><au>Bjørndal, Kristine</au><au>Madsen, Anders Rørbæk</au><au>Jakobsen, John</au><au>Døssing, Helle</au><au>Bay, Mette</au><au>Thomassen, Anders</au><au>Nielsen, Anne Lerberg</au><au>Godballe, Christian</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Risk of Malignancy in FDG-Avid Thyroid Incidentalomas on PET/CT: A Prospective Study</atitle><jtitle>World journal of surgery</jtitle><stitle>World J Surg</stitle><addtitle>World J Surg</addtitle><date>2019-10-15</date><risdate>2019</risdate><volume>43</volume><issue>10</issue><spage>2454</spage><epage>2458</epage><pages>2454-2458</pages><issn>0364-2313</issn><eissn>1432-2323</eissn><abstract>Background
Due to a substantial risk of malignancy, patients with focal FDG-avid thyroid incidentalomas (FFTIs) on PET/CT are in most of Denmark referred to Head and Neck Cancer (HNC) fast track programs. The aim of this study was to determine the risk of malignancy in FFTI managed in a HNC fast track program.
Methods
A prospective cohort study including all patients with FFTI referred to the HNC fast track program, Odense University Hospital between September 1, 2016 and August 31, 2017. Ultrasonography (US) and fine-needle aspiration biopsy (FNAB) were intended to be done in all patients. Nodules with cytology of Bethesda 1, 3, 4, 5, or 6 were planned for surgical removal
.
Results
A total of 104 patients were included. All patients had US and 101 patients (97%) had FNAB. Forty-two patients had benign cytology classified as Bethesda 2. The remaining 62 patients underwent surgery except from 11 patients, mainly due to comorbidity. The overall risk of malignancy for patients with FFTI referred to our HNC fast track program was calculated to be 24% (23/95) based on patients with unequivocal cytology and/or histology. The only statistically significant US characteristic to predict malignancy was the appearance of irregular margins with a sensitivity of 47% and specificity of 96%.
Conclusion
The risk of malignancy of FFTIs handled in our HNC fast track program is 24%.</abstract><cop>Cham</cop><pub>Springer International Publishing</pub><pmid>31161354</pmid><doi>10.1007/s00268-019-05043-6</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0364-2313 |
| ispartof | World journal of surgery, 2019-10, Vol.43 (10), p.2454-2458 |
| issn | 0364-2313 1432-2323 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2235063149 |
| source | MEDLINE; SpringerNature Journals; Access via Wiley Online Library |
| subjects | Abdominal Surgery Adult Aged Aged, 80 and over Algorithms Biopsy Biopsy, Fine-Needle Cardiac Surgery Cellular biology Cytology Denmark Female Fluorodeoxyglucose F18 - metabolism General Surgery Head & neck cancer Health risk assessment Histology Humans Incidental Findings Male Malignancy Medicine Medicine & Public Health Middle Aged Nodules Original Scientific Report Patients Positron Emission Tomography Computed Tomography Prospective Studies Risk Risk management Sensitivity and Specificity Statistical analysis Surgery Thoracic Surgery Thyroid Thyroid gland Thyroid Neoplasms - diagnostic imaging Thyroid Neoplasms - pathology Thyroid Nodule - diagnostic imaging Thyroid Nodule - pathology Ultrasonography Ultrasound Vascular Surgery |
| title | Risk of Malignancy in FDG-Avid Thyroid Incidentalomas on PET/CT: A Prospective Study |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-03T02%3A18%3A56IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Risk%20of%20Malignancy%20in%20FDG-Avid%20Thyroid%20Incidentalomas%20on%20PET/CT:%20A%20Prospective%20Study&rft.jtitle=World%20journal%20of%20surgery&rft.au=Abdel-Halim,%20Chadi%20Nimeh&rft.date=2019-10-15&rft.volume=43&rft.issue=10&rft.spage=2454&rft.epage=2458&rft.pages=2454-2458&rft.issn=0364-2313&rft.eissn=1432-2323&rft_id=info:doi/10.1007/s00268-019-05043-6&rft_dat=%3Cproquest_cross%3E2235063149%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2234287817&rft_id=info:pmid/31161354&rfr_iscdi=true |