Colistin plus meropenem combination is synergistic in vitro against extensively drug-resistant Pseudomonas aeruginosa, including high-risk clones

•Extensively drug resistant (XDR) Pseudomonas aeruginosa causes severe infections.•There is a high risk of resistance selection in these clones.•Colistin has been the only available treatment but that is not an optimal treatment.•Combination regimens could suppress emerging resistance.•Colistin plus...

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Veröffentlicht in:Journal of global antimicrobial resistance. 2019-09, Vol.18, p.37-44
Hauptverfasser: Montero, María M., Domene Ochoa, Sandra, López-Causapé, Carla, VanScoy, Brian, Luque, Sonia, Sorlí, Luisa, Campillo, Núria, Padilla, Eduardo, Prim, Núria, Segura, Concepción, Pomar, Virginia, Rivera, Alba, Grau, Santiago, Ambrose, Paul G., Oliver, Antonio, Horcajada, Juan P.
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Sprache:eng
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