Low Free Triiodothyronine Is Associated with Advanced Fibrosis in Patients at High Risk for Nonalcoholic Steatohepatitis

Background Thyroid hormone is critical for tissue–organ development, growth, differentiation, and metabolism. In murine models of advanced nonalcoholic steatohepatitis (NASH), the administration of T3 reduced liver triglyceride, repressed liver inflammation, and attenuated injury. In recent studies...

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Veröffentlicht in:	Digestive diseases and sciences 2019-08, Vol.64 (8), p.2351-2358
Hauptverfasser:	Manka, Paul, Bechmann, Lars, Best, Jan, Sydor, Svenja, Claridge, Lee C., Coombes, Jason D., Canbay, Ali, Moeller, Lars, Gerken, Guido, Wedemeyer, Heiner, Syn, Wing-Kin
Format:	Artikel
Sprache:	eng
Schlagworte:	Bilirubin Biochemistry Biomarkers - blood Biopsy Clinics Diabetes Down-Regulation Endocrinology Female Fibrosis Gastroenterology Hepatology Hospitals Humans Hypothyroidism Liver Liver Cirrhosis - blood Liver Cirrhosis - diagnostic imaging Liver Cirrhosis - etiology Liver diseases Male Medical research Medicine Medicine & Public Health Medicine, Experimental Metabolism Middle Aged Non-alcoholic Fatty Liver Disease - blood Non-alcoholic Fatty Liver Disease - complications Non-alcoholic Fatty Liver Disease - diagnostic imaging Obesity Oncology Original Article Physiological aspects Prognosis Retrospective Studies Risk Assessment Risk Factors Thyroid gland Thyroid hormones Thyrotropin - blood Thyroxine - blood Transplant Surgery Triglycerides Triiodothyronine - blood Type 2 diabetes Weight control Womens health
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