Determination of Passive Dry Powder Inhaler Aerodynamic Particle Size Distribution by Multi-Stage Cascade Impactor: International Pharmaceutical Aerosol Consortium on Regulation & Science (IPAC-RS) Recommendations to Support Both Product Quality Control and Clinical Programs

ABSTRACT The multi-stage cascade impactor (CI) is the mainstay method for the determination of the aerodynamic particle size distribution (APSD) of aerosols emitted from orally inhaled products (OIPs). CIs are designed to operate at a constant flow rate throughout the measurement process. However, i...

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Veröffentlicht in:	AAPS PharmSciTech 2019-07, Vol.20 (5), p.206-206, Article 206
Hauptverfasser:	Mitchell, Jolyon P., Stein, Stephen W., Doub, William, Goodey, Adrian P., Christopher, J. David, Patel, Rajni B., Tougas, Terrence P., Lyapustina, Svetlana
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Inhalation Aerosols - administration & dosage Aerosols - chemistry Aerosols - standards Biochemistry Biomedical and Life Sciences Biomedicine Biotechnology Dry Powder Inhalers - instrumentation Dry Powder Inhalers - methods Equipment Design - instrumentation Equipment Design - methods Humans Particle Size Pharmacology/Toxicology Pharmacy Powders Quality Control Research Article Respiratory System Agents - administration & dosage Respiratory System Agents - chemistry Respiratory System Agents - standards Technology, Pharmaceutical - methods Theme: Paul Myrdal Memorial Issue - Pharmaceutical Formulation and Aerosol Sciences
Online-Zugang:	Volltext
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