Potential Neuroprotective Effect of miR-451 Against Cerebral Ischemia/Reperfusion Injury in Stroke Patients and a Mouse Model

Recently, microRNAs (miRs) have been reported to be novel regulators in ischemic stroke. In this study, we investigated the pattern of miR-451 expression along with its clinical application in human ischemic stroke and in an in vivo mouse model. The level of miR-451 was evaluated in patients and mic...

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Veröffentlicht in:	World neurosurgery 2019-10, Vol.130, p.e54-e61
Hauptverfasser:	Fu, Chuanyi, Chen, Shuijie, Cai, Nanhua, Liu, Zhaohui, Wang, Pengcheng, Zhao, Jiannong
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Animals Brain ischemia Brain Ischemia - blood Brain Ischemia - complications Disease Models, Animal Female Humans Infarction, Middle Cerebral Artery - blood Male MCAO MicroRNAs - blood Middle Aged miR-451 Neuroprotective Agents - blood Reperfusion Injury - blood Reperfusion Injury - complications Stroke Stroke - blood Stroke - complications
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