Brain tumor classification for MR images using transfer learning and fine-tuning
[Display omitted] The proposed research framework for brain tumor MR images classification using pre-trained deep CNN (VGG19) transfer learning and block-wise fine-tuning. •In this research, we have focused on multiclass brain tumors classification for MR images using pre-trained Convolutional Neura...
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creator | Swati, Zar Nawab Khan Zhao, Qinghua Kabir, Muhammad Ali, Farman Ali, Zakir Ahmed, Saeed Lu, Jianfeng |
description | [Display omitted]
The proposed research framework for brain tumor MR images classification using pre-trained deep CNN (VGG19) transfer learning and block-wise fine-tuning.
•In this research, we have focused on multiclass brain tumors classification for MR images using pre-trained Convolutional Neural Network (CNN) and adopted transfer learning.•To achieve enhance classification results, we proposed block-wise fine-tuning strategy, gradually goes deep down into earlier blocks of the CNN, and monitor the performance improvement.•The proposed method is evaluated on publically available CE-MRI dataset consists of three types of brain tumors (glioma, meningioma, and pituitary) with highest percentage among all brain tumors in clinical practice.•We are using pre-trained CNN because of the small sample size of the CE-MRI dataset.•We have adopted five-fold cross-validation test to ensure the robustness of proposed method. We have performed numerous experiments for brain tumor classification, evaluated the performance of the proposed method, compared our results with state-of-the-art conventional machine learning and deep learning using CNNs for brain tumor classification on the same dataset of CE-MRI.
Accurate and precise brain tumor MR images classification plays important role in clinical diagnosis and decision making for patient treatment. The key challenge in MR images classification is the semantic gap between the low-level visual information captured by the MRI machine and the high-level information perceived by the human evaluator. The traditional machine learning techniques for classification focus only on low-level or high-level features, use some handcrafted features to reduce this gap and require good feature extraction and classification methods. Recent development on deep learning has shown great progress and deep convolution neural networks (CNNs) have succeeded in the images classification task. Deep learning is very powerful for feature representation that can depict low-level and high-level information completely and embed the phase of feature extraction and classification into self-learning but require large training dataset in general. For most of the medical imaging scenario, the training datasets are small, therefore, it is a challenging task to apply the deep learning and train CNN from scratch on the small dataset. Aiming this problem, we use pre-trained deep CNN model and propose a block-wise fine-tuning strategy based on transfer learning. |
doi_str_mv | 10.1016/j.compmedimag.2019.05.001 |
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The proposed research framework for brain tumor MR images classification using pre-trained deep CNN (VGG19) transfer learning and block-wise fine-tuning.
•In this research, we have focused on multiclass brain tumors classification for MR images using pre-trained Convolutional Neural Network (CNN) and adopted transfer learning.•To achieve enhance classification results, we proposed block-wise fine-tuning strategy, gradually goes deep down into earlier blocks of the CNN, and monitor the performance improvement.•The proposed method is evaluated on publically available CE-MRI dataset consists of three types of brain tumors (glioma, meningioma, and pituitary) with highest percentage among all brain tumors in clinical practice.•We are using pre-trained CNN because of the small sample size of the CE-MRI dataset.•We have adopted five-fold cross-validation test to ensure the robustness of proposed method. We have performed numerous experiments for brain tumor classification, evaluated the performance of the proposed method, compared our results with state-of-the-art conventional machine learning and deep learning using CNNs for brain tumor classification on the same dataset of CE-MRI.
Accurate and precise brain tumor MR images classification plays important role in clinical diagnosis and decision making for patient treatment. The key challenge in MR images classification is the semantic gap between the low-level visual information captured by the MRI machine and the high-level information perceived by the human evaluator. The traditional machine learning techniques for classification focus only on low-level or high-level features, use some handcrafted features to reduce this gap and require good feature extraction and classification methods. Recent development on deep learning has shown great progress and deep convolution neural networks (CNNs) have succeeded in the images classification task. Deep learning is very powerful for feature representation that can depict low-level and high-level information completely and embed the phase of feature extraction and classification into self-learning but require large training dataset in general. For most of the medical imaging scenario, the training datasets are small, therefore, it is a challenging task to apply the deep learning and train CNN from scratch on the small dataset. Aiming this problem, we use pre-trained deep CNN model and propose a block-wise fine-tuning strategy based on transfer learning. The proposed method is evaluated on T1-weighted contrast-enhanced magnetic resonance images (CE-MRI) benchmark dataset. Our method is more generic as it does not use any handcrafted features, requires minimal preprocessing and can achieve average accuracy of 94.82% under five-fold cross-validation. We compare our results not only with the traditional machine learning but also with deep learning methods using CNNs. Experimental results show that our proposed method outperforms state-of-the-art classification on the CE-MRI dataset.</description><identifier>ISSN: 0895-6111</identifier><identifier>EISSN: 1879-0771</identifier><identifier>DOI: 10.1016/j.compmedimag.2019.05.001</identifier><identifier>PMID: 31150950</identifier><language>eng</language><publisher>United States: Elsevier Ltd</publisher><subject>Artificial intelligence ; Artificial neural networks ; Block-wise fine-tuning ; Brain ; Brain cancer ; Brain tumor classification ; Brain tumors ; Classification ; Clinical decision making ; Convolution ; Convolutional neural networks ; Datasets ; Decision making ; Deep learning ; Feature extraction ; Image classification ; Image contrast ; Image enhancement ; Learning algorithms ; Machine learning ; Magnetic resonance images ; Magnetic resonance imaging ; Medical imaging ; Neural networks ; Neuroimaging ; Training ; Transfer learning ; Tumors ; Tuning ; Visual perception</subject><ispartof>Computerized medical imaging and graphics, 2019-07, Vol.75, p.34-46</ispartof><rights>2019 Elsevier Ltd</rights><rights>Copyright © 2019 Elsevier Ltd. All rights reserved.</rights><rights>Copyright Elsevier Science Ltd. Jul 2019</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c471t-6965d2ca3746f79b0c3771a2382653318142d570f46fcadaedddfecb78bf1bcc3</citedby><cites>FETCH-LOGICAL-c471t-6965d2ca3746f79b0c3771a2382653318142d570f46fcadaedddfecb78bf1bcc3</cites><orcidid>0000-0002-9190-507X ; 0000-0002-2488-1653 ; 0000-0002-0914-1577</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0895611118305937$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31150950$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Swati, Zar Nawab Khan</creatorcontrib><creatorcontrib>Zhao, Qinghua</creatorcontrib><creatorcontrib>Kabir, Muhammad</creatorcontrib><creatorcontrib>Ali, Farman</creatorcontrib><creatorcontrib>Ali, Zakir</creatorcontrib><creatorcontrib>Ahmed, Saeed</creatorcontrib><creatorcontrib>Lu, Jianfeng</creatorcontrib><title>Brain tumor classification for MR images using transfer learning and fine-tuning</title><title>Computerized medical imaging and graphics</title><addtitle>Comput Med Imaging Graph</addtitle><description>[Display omitted]
The proposed research framework for brain tumor MR images classification using pre-trained deep CNN (VGG19) transfer learning and block-wise fine-tuning.
•In this research, we have focused on multiclass brain tumors classification for MR images using pre-trained Convolutional Neural Network (CNN) and adopted transfer learning.•To achieve enhance classification results, we proposed block-wise fine-tuning strategy, gradually goes deep down into earlier blocks of the CNN, and monitor the performance improvement.•The proposed method is evaluated on publically available CE-MRI dataset consists of three types of brain tumors (glioma, meningioma, and pituitary) with highest percentage among all brain tumors in clinical practice.•We are using pre-trained CNN because of the small sample size of the CE-MRI dataset.•We have adopted five-fold cross-validation test to ensure the robustness of proposed method. We have performed numerous experiments for brain tumor classification, evaluated the performance of the proposed method, compared our results with state-of-the-art conventional machine learning and deep learning using CNNs for brain tumor classification on the same dataset of CE-MRI.
Accurate and precise brain tumor MR images classification plays important role in clinical diagnosis and decision making for patient treatment. The key challenge in MR images classification is the semantic gap between the low-level visual information captured by the MRI machine and the high-level information perceived by the human evaluator. The traditional machine learning techniques for classification focus only on low-level or high-level features, use some handcrafted features to reduce this gap and require good feature extraction and classification methods. Recent development on deep learning has shown great progress and deep convolution neural networks (CNNs) have succeeded in the images classification task. Deep learning is very powerful for feature representation that can depict low-level and high-level information completely and embed the phase of feature extraction and classification into self-learning but require large training dataset in general. For most of the medical imaging scenario, the training datasets are small, therefore, it is a challenging task to apply the deep learning and train CNN from scratch on the small dataset. Aiming this problem, we use pre-trained deep CNN model and propose a block-wise fine-tuning strategy based on transfer learning. The proposed method is evaluated on T1-weighted contrast-enhanced magnetic resonance images (CE-MRI) benchmark dataset. Our method is more generic as it does not use any handcrafted features, requires minimal preprocessing and can achieve average accuracy of 94.82% under five-fold cross-validation. We compare our results not only with the traditional machine learning but also with deep learning methods using CNNs. Experimental results show that our proposed method outperforms state-of-the-art classification on the CE-MRI dataset.</description><subject>Artificial intelligence</subject><subject>Artificial neural networks</subject><subject>Block-wise fine-tuning</subject><subject>Brain</subject><subject>Brain cancer</subject><subject>Brain tumor classification</subject><subject>Brain tumors</subject><subject>Classification</subject><subject>Clinical decision making</subject><subject>Convolution</subject><subject>Convolutional neural networks</subject><subject>Datasets</subject><subject>Decision making</subject><subject>Deep learning</subject><subject>Feature extraction</subject><subject>Image classification</subject><subject>Image contrast</subject><subject>Image enhancement</subject><subject>Learning algorithms</subject><subject>Machine learning</subject><subject>Magnetic resonance images</subject><subject>Magnetic resonance imaging</subject><subject>Medical imaging</subject><subject>Neural networks</subject><subject>Neuroimaging</subject><subject>Training</subject><subject>Transfer learning</subject><subject>Tumors</subject><subject>Tuning</subject><subject>Visual perception</subject><issn>0895-6111</issn><issn>1879-0771</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><recordid>eNqNkEtv1DAQgC0EokvhL6AgLlySztjrR46w4iW1oqrgbDl-VF4lzmInSPx7HG1BiBMnyzPfvD5CXiF0CCiujp2dp9PkXZzMfUcB-w54B4CPyA6V7FuQEh-THaietwIRL8izUo4AQEHiU3LBEDn0HHbk9l02MTXLOs25saMpJYZozRLn1IQaurlrtiG-NGuJ6b5Zskkl-NyM3uS0RUxyTYjJt8u6_Z-TJ8GMxb94eC_Jtw_vvx4-tddfPn4-vL1u7V7i0opecEetYXIvguwHsKzubChTVHDGUOGeOi4h1LQ1znjnXPB2kGoIOFjLLsmbc99Tnr-vvix6isX6cTTJz2vRlDKmOFVcVfT1P-hxXnOq21VKKKFQSFqp_kzZPJeSfdCnXE_PPzWC3rTro_5Lu960a-C6aq-1Lx8mrEPN_6n87bkChzPgq5If0WddbPTJ1l7Z20W7Of7HmF-F3ZmD</recordid><startdate>201907</startdate><enddate>201907</enddate><creator>Swati, Zar Nawab Khan</creator><creator>Zhao, Qinghua</creator><creator>Kabir, Muhammad</creator><creator>Ali, Farman</creator><creator>Ali, Zakir</creator><creator>Ahmed, Saeed</creator><creator>Lu, Jianfeng</creator><general>Elsevier Ltd</general><general>Elsevier Science Ltd</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>7SC</scope><scope>8FD</scope><scope>FR3</scope><scope>JQ2</scope><scope>K9.</scope><scope>L7M</scope><scope>L~C</scope><scope>L~D</scope><scope>NAPCQ</scope><scope>P64</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-9190-507X</orcidid><orcidid>https://orcid.org/0000-0002-2488-1653</orcidid><orcidid>https://orcid.org/0000-0002-0914-1577</orcidid></search><sort><creationdate>201907</creationdate><title>Brain tumor classification for MR images using transfer learning and fine-tuning</title><author>Swati, Zar Nawab Khan ; Zhao, Qinghua ; Kabir, Muhammad ; Ali, Farman ; Ali, Zakir ; Ahmed, Saeed ; Lu, Jianfeng</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c471t-6965d2ca3746f79b0c3771a2382653318142d570f46fcadaedddfecb78bf1bcc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Artificial intelligence</topic><topic>Artificial neural networks</topic><topic>Block-wise fine-tuning</topic><topic>Brain</topic><topic>Brain cancer</topic><topic>Brain tumor classification</topic><topic>Brain tumors</topic><topic>Classification</topic><topic>Clinical decision making</topic><topic>Convolution</topic><topic>Convolutional neural networks</topic><topic>Datasets</topic><topic>Decision making</topic><topic>Deep learning</topic><topic>Feature extraction</topic><topic>Image classification</topic><topic>Image contrast</topic><topic>Image enhancement</topic><topic>Learning algorithms</topic><topic>Machine learning</topic><topic>Magnetic resonance images</topic><topic>Magnetic resonance imaging</topic><topic>Medical imaging</topic><topic>Neural networks</topic><topic>Neuroimaging</topic><topic>Training</topic><topic>Transfer learning</topic><topic>Tumors</topic><topic>Tuning</topic><topic>Visual perception</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Swati, Zar Nawab Khan</creatorcontrib><creatorcontrib>Zhao, Qinghua</creatorcontrib><creatorcontrib>Kabir, Muhammad</creatorcontrib><creatorcontrib>Ali, Farman</creatorcontrib><creatorcontrib>Ali, Zakir</creatorcontrib><creatorcontrib>Ahmed, Saeed</creatorcontrib><creatorcontrib>Lu, Jianfeng</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Computer and Information Systems Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>ProQuest Computer Science Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>Computer and Information Systems Abstracts Academic</collection><collection>Computer and Information Systems Abstracts Professional</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Computerized medical imaging and graphics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Swati, Zar Nawab Khan</au><au>Zhao, Qinghua</au><au>Kabir, Muhammad</au><au>Ali, Farman</au><au>Ali, Zakir</au><au>Ahmed, Saeed</au><au>Lu, Jianfeng</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Brain tumor classification for MR images using transfer learning and fine-tuning</atitle><jtitle>Computerized medical imaging and graphics</jtitle><addtitle>Comput Med Imaging Graph</addtitle><date>2019-07</date><risdate>2019</risdate><volume>75</volume><spage>34</spage><epage>46</epage><pages>34-46</pages><issn>0895-6111</issn><eissn>1879-0771</eissn><abstract>[Display omitted]
The proposed research framework for brain tumor MR images classification using pre-trained deep CNN (VGG19) transfer learning and block-wise fine-tuning.
•In this research, we have focused on multiclass brain tumors classification for MR images using pre-trained Convolutional Neural Network (CNN) and adopted transfer learning.•To achieve enhance classification results, we proposed block-wise fine-tuning strategy, gradually goes deep down into earlier blocks of the CNN, and monitor the performance improvement.•The proposed method is evaluated on publically available CE-MRI dataset consists of three types of brain tumors (glioma, meningioma, and pituitary) with highest percentage among all brain tumors in clinical practice.•We are using pre-trained CNN because of the small sample size of the CE-MRI dataset.•We have adopted five-fold cross-validation test to ensure the robustness of proposed method. We have performed numerous experiments for brain tumor classification, evaluated the performance of the proposed method, compared our results with state-of-the-art conventional machine learning and deep learning using CNNs for brain tumor classification on the same dataset of CE-MRI.
Accurate and precise brain tumor MR images classification plays important role in clinical diagnosis and decision making for patient treatment. The key challenge in MR images classification is the semantic gap between the low-level visual information captured by the MRI machine and the high-level information perceived by the human evaluator. The traditional machine learning techniques for classification focus only on low-level or high-level features, use some handcrafted features to reduce this gap and require good feature extraction and classification methods. Recent development on deep learning has shown great progress and deep convolution neural networks (CNNs) have succeeded in the images classification task. Deep learning is very powerful for feature representation that can depict low-level and high-level information completely and embed the phase of feature extraction and classification into self-learning but require large training dataset in general. For most of the medical imaging scenario, the training datasets are small, therefore, it is a challenging task to apply the deep learning and train CNN from scratch on the small dataset. Aiming this problem, we use pre-trained deep CNN model and propose a block-wise fine-tuning strategy based on transfer learning. The proposed method is evaluated on T1-weighted contrast-enhanced magnetic resonance images (CE-MRI) benchmark dataset. Our method is more generic as it does not use any handcrafted features, requires minimal preprocessing and can achieve average accuracy of 94.82% under five-fold cross-validation. We compare our results not only with the traditional machine learning but also with deep learning methods using CNNs. Experimental results show that our proposed method outperforms state-of-the-art classification on the CE-MRI dataset.</abstract><cop>United States</cop><pub>Elsevier Ltd</pub><pmid>31150950</pmid><doi>10.1016/j.compmedimag.2019.05.001</doi><tpages>13</tpages><orcidid>https://orcid.org/0000-0002-9190-507X</orcidid><orcidid>https://orcid.org/0000-0002-2488-1653</orcidid><orcidid>https://orcid.org/0000-0002-0914-1577</orcidid></addata></record> |
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subjects | Artificial intelligence Artificial neural networks Block-wise fine-tuning Brain Brain cancer Brain tumor classification Brain tumors Classification Clinical decision making Convolution Convolutional neural networks Datasets Decision making Deep learning Feature extraction Image classification Image contrast Image enhancement Learning algorithms Machine learning Magnetic resonance images Magnetic resonance imaging Medical imaging Neural networks Neuroimaging Training Transfer learning Tumors Tuning Visual perception |
title | Brain tumor classification for MR images using transfer learning and fine-tuning |
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