Computational de-orphanization of the olive oil biophenol oleacein: Discovery of new metabolic and epigenetic targets

The health promoting effects of extra virgin olive oil (EVOO) relate to its unique repertoire of phenolic compounds. Here, we used a chemoinformatics approach to computationally identify endogenous ligands and assign putative biomolecular targets to oleacein, one of the most abundant secoiridoids in...

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Veröffentlicht in:	Food and chemical toxicology 2019-09, Vol.131, p.110529-110529, Article 110529
Hauptverfasser:	Cuyàs, Elisabet, Castillo, David, Llorach-Parés, Laura, Lozano-Sánchez, Jesús, Verdura, Sara, Nonell-Canals, Alfons, Brunet, Joan, Bosch-Barrera, Joaquim, Joven, Jorge, Valdés, Rafael, Sanchez-Martinez, Melchor, Segura-Carretero, Antonio, Menendez, Javier A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemoinformatics Epigenetics Metabolism Oleacein Olive oil
Online-Zugang:	Volltext
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