Meta-analysis: compared with anti-CCP and rheumatoid factor, could anti-MCV be the next biomarker in the rheumatoid arthritis classification criteria?

Background Previous reviews of the diagnosis for rheumatoid arthritis (RA) have not compared anti-mutated citrullinated vimentin (MCV) with anti-cyclic citrullinated peptide (CCP) and rheumatoid factor (RF) in respect of sensitivity, specificity and the area under the curve (AUC) against disease con...

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Veröffentlicht in:	Clinical chemistry and laboratory medicine 2019-10, Vol.57 (11), p.1668-1679
Hauptverfasser:	Zhu, Jia-Ning, Nie, Liu-Yan, Lu, Xiao-Yong, Wu, Hua-Xiang
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Citrullinated Protein Antibodies - metabolism anti-cyclic citrullinated peptide antibodies anti-mutated citrullinated vimentin antibodies Arthritis Arthritis, Rheumatoid - blood Arthritis, Rheumatoid - diagnosis Biomarkers Bivariate analysis Citrulline Criteria Diagnosis Diagnostic systems Differential diagnosis Disease control Female Heterogeneity Humans Immunologic Tests - methods Male Meta-analysis Peptides, Cyclic - immunology Rheumatoid arthritis Rheumatoid factor Rheumatoid Factor - immunology Sensitivity analysis Statistical analysis Vimentin Vimentin - immunology
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