Predicting Cognitive Decline and Dementia with the Newly Normed SKT Short Cognitive Performance Test
Objective: The aim of this article was to determine the criterion-related validity of the newly normed SKT (Syndrom-Kurztest) Short Cognitive Performance Test with the onset of dementia as the predicted criterion. Methods: The cognitive ability was tested with the SKT in a sample of 546 cognitively...
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Veröffentlicht in: | Dementia and Geriatric Cognitive Disorders Extra 2019-01, Vol.9 (1), p.184-193 |
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description | Objective: The aim of this article was to determine the criterion-related validity of the newly normed SKT (Syndrom-Kurztest) Short Cognitive Performance Test with the onset of dementia as the predicted criterion. Methods: The cognitive ability was tested with the SKT in a sample of 546 cognitively healthy adults aged 65–85 years. New cases of mild cognitive impairment (MCI) or dementia were determined in 3 follow-up investigations at 1-year intervals. Each participant’s cognitive status was rated on the Clinical Dementia Rating Scale. The cognitive status according to the SKT is presented in terms of a traffic light system. Results: Based on Kaplan-Meier estimators, the trajectories of the different SKT traffic light labels were investigated over 3 years. The trajectories were significantly different, representing differential risks for dementia onset. In comparison to the green group, the hazard ratio (HR) for the development of dementia and MCI amounted to HR 6.63 (95% CI 2.75–15.96) and HR 2.34 (95% CI 1.37–3.99), respectively, in the yellow group, and to HR 25.40 (95% CI 10.73–60.14) and HR 3.83 (95% CI 1.86–7.86), respectively, in the red group. Conclusions: The newly normed SKT showed a high predictive validity for the onset of dementia. |
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Methods: The cognitive ability was tested with the SKT in a sample of 546 cognitively healthy adults aged 65–85 years. New cases of mild cognitive impairment (MCI) or dementia were determined in 3 follow-up investigations at 1-year intervals. Each participant’s cognitive status was rated on the Clinical Dementia Rating Scale. The cognitive status according to the SKT is presented in terms of a traffic light system. Results: Based on Kaplan-Meier estimators, the trajectories of the different SKT traffic light labels were investigated over 3 years. The trajectories were significantly different, representing differential risks for dementia onset. In comparison to the green group, the hazard ratio (HR) for the development of dementia and MCI amounted to HR 6.63 (95% CI 2.75–15.96) and HR 2.34 (95% CI 1.37–3.99), respectively, in the yellow group, and to HR 25.40 (95% CI 10.73–60.14) and HR 3.83 (95% CI 1.86–7.86), respectively, in the red group. Conclusions: The newly normed SKT showed a high predictive validity for the onset of dementia.</description><identifier>ISSN: 1664-5464</identifier><identifier>EISSN: 1664-5464</identifier><identifier>DOI: 10.1159/000497308</identifier><identifier>PMID: 31123461</identifier><language>eng</language><publisher>Basel, Switzerland: S. Karger AG</publisher><subject>Adults ; Alzheimer's disease ; Care and treatment ; Cognitive ability ; Cognitive development ; Cognitive impairment ; Cognitive tests ; Cox regression ; Dementia ; Diagnosis ; Environmental associations ; Health aspects ; Hospitals ; Medical research ; Memory ; Mild cognitive impairment ; Older people ; Original ; Original Research Article ; Predictive validity ; SKT (Syndrom Kurztest)</subject><ispartof>Dementia and Geriatric Cognitive Disorders Extra, 2019-01, Vol.9 (1), p.184-193</ispartof><rights>2019 The Author(s) Published by S. Karger AG, Basel</rights><rights>COPYRIGHT 2019 S. Karger AG</rights><rights>Copyright © 2019 by S. Karger AG, Basel 2019</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c585t-76a6c604f1013b8957648dcfd0cec404872733b1200e0f4de7767db01ab5d58d3</citedby><cites>FETCH-LOGICAL-c585t-76a6c604f1013b8957648dcfd0cec404872733b1200e0f4de7767db01ab5d58d3</cites><orcidid>0000-0003-4321-1302</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514486/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514486/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,2096,27612,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31123461$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Stemmler, Mark</creatorcontrib><creatorcontrib>Hessler, Johannes Baltasar</creatorcontrib><creatorcontrib>Bickel, Horst</creatorcontrib><title>Predicting Cognitive Decline and Dementia with the Newly Normed SKT Short Cognitive Performance Test</title><title>Dementia and Geriatric Cognitive Disorders Extra</title><addtitle>Dement Geriatr Cogn Disord Extra</addtitle><description>Objective: The aim of this article was to determine the criterion-related validity of the newly normed SKT (Syndrom-Kurztest) Short Cognitive Performance Test with the onset of dementia as the predicted criterion. Methods: The cognitive ability was tested with the SKT in a sample of 546 cognitively healthy adults aged 65–85 years. New cases of mild cognitive impairment (MCI) or dementia were determined in 3 follow-up investigations at 1-year intervals. Each participant’s cognitive status was rated on the Clinical Dementia Rating Scale. The cognitive status according to the SKT is presented in terms of a traffic light system. Results: Based on Kaplan-Meier estimators, the trajectories of the different SKT traffic light labels were investigated over 3 years. The trajectories were significantly different, representing differential risks for dementia onset. In comparison to the green group, the hazard ratio (HR) for the development of dementia and MCI amounted to HR 6.63 (95% CI 2.75–15.96) and HR 2.34 (95% CI 1.37–3.99), respectively, in the yellow group, and to HR 25.40 (95% CI 10.73–60.14) and HR 3.83 (95% CI 1.86–7.86), respectively, in the red group. Conclusions: The newly normed SKT showed a high predictive validity for the onset of dementia.</description><subject>Adults</subject><subject>Alzheimer's disease</subject><subject>Care and treatment</subject><subject>Cognitive ability</subject><subject>Cognitive development</subject><subject>Cognitive impairment</subject><subject>Cognitive tests</subject><subject>Cox regression</subject><subject>Dementia</subject><subject>Diagnosis</subject><subject>Environmental associations</subject><subject>Health aspects</subject><subject>Hospitals</subject><subject>Medical research</subject><subject>Memory</subject><subject>Mild cognitive impairment</subject><subject>Older people</subject><subject>Original</subject><subject>Original Research Article</subject><subject>Predictive validity</subject><subject>SKT (Syndrom Kurztest)</subject><issn>1664-5464</issn><issn>1664-5464</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>M--</sourceid><sourceid>BENPR</sourceid><sourceid>DOA</sourceid><recordid>eNptkk1vEzEQQFcIRKvSA3eEVuICh5Tx-mPXF6QqDVBRlUoNZ8uxxxuHjR28m1b99zhNCClCPtgaP7_xjKYoXhM4I4TLjwDAZE2heVYcEyHYiDPBnh-cj4rTvl9kDDiXTLKXxRElpKJMkOPC3iS03gw-tOU4tsEP_g7LCzSdD1jqYPN5iWHwurz3w7wc5lhe4333UF7HtERb3n6blrfzmIaD5zeYXL7VwWA5xX54VbxwuuvxdLefFD8-T6bjr6Or718ux-dXI8MbPoxqoYURwBwBQmeN5LVgjTXOgkHDgDV1VVM6IxUAgmMW61rUdgZEz7jljaUnxeXWa6NeqFXyS50eVNRePQZiapVOgzcdKsY1ctPIykrJHOjGYQ3a5tTQGBQb16eta7We5TpN7kHS3RPp05vg56qNd0pwwlgjsuD9TpDir3Xuglr63mDX6YBx3auqohWhjBGZ0Xf_oIu4TiG3SlUUiIS6ehSebalW5wJ8cDHnNXlZXHoTAzqf4-dcUkYJhY32w_aBSbHvE7r97wmozeyo_exk9u1huXvyz6T8_eNPnVpMe-BiMtkq1Mq6TL35L7XL8hsPetIZ</recordid><startdate>20190101</startdate><enddate>20190101</enddate><creator>Stemmler, Mark</creator><creator>Hessler, Johannes Baltasar</creator><creator>Bickel, Horst</creator><general>S. 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Methods: The cognitive ability was tested with the SKT in a sample of 546 cognitively healthy adults aged 65–85 years. New cases of mild cognitive impairment (MCI) or dementia were determined in 3 follow-up investigations at 1-year intervals. Each participant’s cognitive status was rated on the Clinical Dementia Rating Scale. The cognitive status according to the SKT is presented in terms of a traffic light system. Results: Based on Kaplan-Meier estimators, the trajectories of the different SKT traffic light labels were investigated over 3 years. The trajectories were significantly different, representing differential risks for dementia onset. In comparison to the green group, the hazard ratio (HR) for the development of dementia and MCI amounted to HR 6.63 (95% CI 2.75–15.96) and HR 2.34 (95% CI 1.37–3.99), respectively, in the yellow group, and to HR 25.40 (95% CI 10.73–60.14) and HR 3.83 (95% CI 1.86–7.86), respectively, in the red group. 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subjects | Adults Alzheimer's disease Care and treatment Cognitive ability Cognitive development Cognitive impairment Cognitive tests Cox regression Dementia Diagnosis Environmental associations Health aspects Hospitals Medical research Memory Mild cognitive impairment Older people Original Original Research Article Predictive validity SKT (Syndrom Kurztest) |
title | Predicting Cognitive Decline and Dementia with the Newly Normed SKT Short Cognitive Performance Test |
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