Effect of probiotics on gastrointestinal symptoms and immune parameters in systemic sclerosis: a randomized placebo-controlled trial

Abstract Objectives Changes in the intestinal microbiota have been associated with the pathogenesis of SSc. Probiotics act by modulating the microbiome and the immune response. This study aimed to evaluate the efficacy of probiotics on gastrointestinal (GI) symptoms and immune responses in SSc patie...

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Veröffentlicht in:	Rheumatology (Oxford, England) England), 2019-11, Vol.58 (11), p.1985-1990
Hauptverfasser:	Marighela, Thais Fernandes, Arismendi, Maria Izabel, Marvulle, Valdecir, Brunialti, Milena Karina Coló, Salomão, Reinaldo, Kayser, Cristiane
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Disability Evaluation Double-Blind Method Female Gastrointestinal Diseases - etiology Gastrointestinal Diseases - microbiology Gastrointestinal Diseases - therapy Gastrointestinal Microbiome - immunology Gastrointestinal Tract - immunology Gastrointestinal Tract - microbiology Humans Male Middle Aged Probiotics - therapeutic use Scleroderma, Systemic - complications Scleroderma, Systemic - immunology Scleroderma, Systemic - microbiology Severity of Illness Index T-Lymphocytes - metabolism T-Lymphocytes - microbiology Treatment Outcome
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