Elevation of the vitreous body concentrations of oxidative stress-responsive apoptosis-inducing protein (ORAIP) in proliferative diabetic retinopathy

Purpose Oxidative stress has been implicated in the pathogenesis of various disorders, including diabetic retinopathy (DR). Oxidative stress-responsive apoptosis-inducing protein (ORAIP; a tyrosine-sulfated secreted form of eukaryotic translation initiation factor 5A [eIF5A]) is a recently discovere...

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Veröffentlicht in:	Graefe's archive for clinical and experimental ophthalmology 2019-07, Vol.257 (7), p.1519-1525
Hauptverfasser:	Suzuki, Yuta, Yao, Takako, Okumura, Ko, Seko, Yoshinori, Kitano, Shigehiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Autocrine signalling Chemokines Cytotoxicity Diabetes Diabetes mellitus Diabetic retinopathy Enzyme-linked immunosorbent assay Initiation factor eIF-5A Interleukin 6 Interleukin 8 Ligands Medical Ophthalmology Medicine Medicine & Public Health Monocyte chemoattractant protein 1 Ophthalmology Oxidative stress Retina Retinopathy Therapeutic applications Tyrosine Vascular endothelial growth factor
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