NMR metabolomics to study the metabolic response of human osteoblasts to non‐poled and poled poly (L‐lactic) acid

Untargeted nuclear magnetic resonance (NMR) metabolomics was employed, for the first time to our knowledge, to characterize the metabolome of human osteoblast (HOb) cells and extracts in the presence of non‐poled or negatively poled poly‐L‐lactic acid (PLLA). The metabolic response of these cells to...

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Veröffentlicht in:	Magnetic resonance in chemistry 2019-11, Vol.57 (11), p.919-933
Hauptverfasser:	Araújo, Rita, Carneiro, Tatiana J., Marinho, Paula, Costa, Marisa Maltez, Roque, Ana, Cruz e Silva, Odete A. B., Fernandes, Maria Helena, Vilarinho, Paula M., Gil, Ana M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomedical materials Biosynthesis Catabolism Cell growth Cell Proliferation Deoxidizing Energy storage Human behavior Humans Lactic acid Lipids Magnetic Resonance Spectroscopy Metabolism Metabolomics NMR Nuclear magnetic resonance Osteoblasts Osteoblasts - cytology Osteoblasts - metabolism piezoelectricity poling Polyesters - chemistry Polyesters - metabolism poly‐L‐lactic acid (PLLA) Regeneration (physiology) Tissue engineering tissue regeneration
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