Directional stimulation of subthalamic nucleus sweet spot predicts clinical efficacy: Proof of concept

Directional deep brain stimulation (dDBS) of the subthalamic nucleus for Parkinson's disease (PD) increases the therapeutic window. However, empirical programming of the neurostimulator becomes more complex given the increasing number of stimulation parameters. A better understanding of dDBS is...

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Veröffentlicht in:	Brain stimulation 2019-09, Vol.12 (5), p.1127-1134
Hauptverfasser:	Nguyen, T.A. Khoa, Nowacki, Andreas, Debove, Ines, Petermann, Katrin, Tinkhauser, Gerd, Wiest, Roland, Schüpbach, Michael, Krack, Paul, Pollo, Claudio
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Algorithms Brain Mapping - methods Deep brain stimulation Deep Brain Stimulation - methods Directional electrode Female Humans Male Middle Aged Parkinson Disease - therapy Parkinson's disease Predictive Value of Tests Probabilistic stimulation map Proof of Concept Study Prospective Studies Subthalamic Nucleus - physiology Treatment Outcome Volume of tissue activated
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