Effect of Montelukast, a Cysteinyl Leukotriene Receptor-1 Antagonist, on a Rat Model of Acute Bacterial Sinonasal Inflammation

Aim This study aimed to investigate montelukast (MONT), a leukotriene receptor antagonist, as a potential treatment protocol and/or supportive therapy against acute bacterial sinonasal inflammation by histopathological and molecular analyses. Material and Methods A total of 30 rats were used in the...

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Veröffentlicht in:	American journal of rhinology & allergy 2019-09, Vol.33 (5), p.559-566
Hauptverfasser:	Kaya, Zülküf, Yayla, Muhammed, Cinar, Irfan, Celebi, Demet, Toktay, Erdem, Bayraktutan, Zafer, Bilici, Dilek
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetates - administration & dosage Animals Anti-Bacterial Agents - administration & dosage Cefazolin - administration & dosage Cytokines - genetics Cytokines - metabolism Disease Models, Animal Inflammation Leukotriene Antagonists - administration & dosage Male Nasal Septum - drug effects Nasal Septum - immunology Nasal Septum - pathology Quinolines - administration & dosage Rats Rats, Wistar Rhinitis - drug therapy Rhinitis - immunology Rhinitis - pathology Sinusitis - drug therapy Sinusitis - immunology Sinusitis - pathology Staphylococcal Infections - drug therapy Staphylococcal Infections - immunology Staphylococcal Infections - pathology Staphylococcus aureus - drug effects Treatment Outcome Turbinates - drug effects Turbinates - immunology Turbinates - pathology
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