Tanycyte-Like Cells Derived From Mouse Embryonic Stem Culture Show Hypothalamic Neural Stem/Progenitor Cell Functions

Abstract Tanycytes have recently been accepted as neural stem/progenitor cells in the postnatal hypothalamus. Persistent retina and anterior neural fold homeobox (Rax) expression is characteristic of tanycytes in contrast to its transient expression of whole hypothalamic precursors. In this study, w...

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Veröffentlicht in:	Endocrinology (Philadelphia) 2019-07, Vol.160 (7), p.1701-1718
Hauptverfasser:	Kano, Mayuko, Suga, Hidetaka, Ishihara, Takeshi, Sakakibara, Mayu, Soen, Mika, Yamada, Tomiko, Ozaki, Hajime, Mitsumoto, Kazuki, Kasai, Takatoshi, Sugiyama, Mariko, Onoue, Takeshi, Tsunekawa, Taku, Takagi, Hiroshi, Hagiwara, Daisuke, Ito, Yoshihiro, Iwama, Shintaro, Goto, Motomitsu, Banno, Ryoichi, Arima, Hiroshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Astrocytes Cell culture Cell differentiation Cell Lineage - physiology Cells, Cultured Differentiation Embryonic stem cells Embryonic Stem Cells - cytology Embryonic Stem Cells - metabolism Endocrinology Ependymoglial Cells - cytology Ependymoglial Cells - metabolism Epithelial cells Fibroblast growth factor 10 Fibroblast Growth Factor 10 - metabolism Fibroblast growth factor 18 Fibroblast growth factor 2 Fibroblast Growth Factors - metabolism Glial cells Growth Homeobox Hypothalamus Hypothalamus (anterior) Hypothalamus - cytology Hypothalamus - metabolism LIM-Homeodomain Proteins - metabolism Maturation Methods Mice Nestin Neural stem cells Neural Stem Cells - cytology Neural Stem Cells - metabolism Neuronal-glial interactions Neurons Neuropeptide Y Neurospheres Nuclei (cytology) Oligodendrocytes Physiological aspects Polymerase chain reaction Progenitor cells Regenerative medicine Retina Stem cells Tanycytes Transcription Factors - metabolism Vimentin
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