Synthesis of Indoles through Domino Reactions of 2‐Fluorotoluenes and Nitriles

Indoles are essential heterocycles in medicinal chemistry, and therefore, novel and efficient approaches to their synthesis are in high demand. Among indoles, 2‐aryl indoles have been described as privileged scaffolds. Advanced herein is a straightforward, practical, and transition‐metal‐free assemb...

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Veröffentlicht in:	Angewandte Chemie International Edition 2019-08, Vol.58 (32), p.11033-11038
Hauptverfasser:	Mao, Jianyou, Wang, Zhiting, Xu, Xinyu, Liu, Guoqing, Jiang, Runsheng, Guan, Haixing, Zheng, Zhipeng, Walsh, Patrick J.
Format:	Artikel
Sprache:	eng
Schlagworte:	2-fluorotoluenes Aromatic compounds Cascade chemical reactions Cesium fluorides Cyanide domino reactions Indoles Nitriles nitrogen heterocycles Organic chemistry
Online-Zugang:	Volltext
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