Zolmitriptan attenuates hepatocellular carcinoma via activation of caspase mediated apoptosis

A preclinical study using DEN-induced HCC rat model was attempted to evaluate the antitumor potential of zolmitriptan (ZOL). The molecular insights were investigated using ELISA, qRT-PCR and Western blot techniques. The result confirmed that the HCC condition was developed in response to lower expre...

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Veröffentlicht in:	Chemico-biological interactions 2019-08, Vol.308, p.120-129
Hauptverfasser:	Maurya, Vimal, Kumar, Pranesh, Chakraborti, Sreemoyee, Singh, Ashok K., Bhadauria, Archana S., Kumar, Umesh, Kumar, Dinesh, Pramanik, Arnab, Saha, Biswajit, Kumar R, Venkatesh, Gosipatala, Sunil Babu, Bhattachariya, Bolay, Maity, Biswanath, Saha, Sudipta
Format:	Artikel
Sprache:	eng
Schlagworte:	1H-NMR based metabolomics Hepatocellular carcinoma Mitochondrial apoptosis Zolmitriptan
Online-Zugang:	Volltext
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