Questions associated with the development of novel drugs intended for the treatment of bacterial infections in veterinary species

[Display omitted] •Drugs acting through effects on antivirulence targets present a novel approach for reducing the pathological effects of bacterial infections.•Impacting the development of these drugs for animals are the many uncertainties associated with the questions that need to be addressed.•Th...

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Veröffentlicht in:	The veterinary journal (1997) 2019-06, Vol.248, p.79-85
Hauptverfasser:	Martinez, Marilyn N., Watts, Jeffrey L., Gilbert, Jeffrey M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Bacterial Agents - pharmacology Anti-Bacterial Agents - therapeutic use Antivirulence targets Bacterial Infections - drug therapy Bacterial Infections - microbiology Bacterial Infections - veterinary Drug Resistance, Multiple, Bacterial Drugs, Investigational Effectiveness assessments Regulatory challenges Resistance issues Safety considerations Virulence Factors
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