A coupled physical-computational methodology for the investigation of short fall related infant head impact injury
•Head model simulated global impact response of infant cadaver and physical model.•Regions of head produced significantly greater accelerations than global response.•Majority of strain within relatively elastic suture and fontanelle regions.•Head model, produced good qualitative match with cadaver f...
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description | •Head model simulated global impact response of infant cadaver and physical model.•Regions of head produced significantly greater accelerations than global response.•Majority of strain within relatively elastic suture and fontanelle regions.•Head model, produced good qualitative match with cadaver fracture risk.•Parametric analysis correlated fall height with stress-response and fracture-risk.
Head injury in childhood is the most common cause of death or permanent disability from injury. However, insufficient understanding exists of the response of a child’s head to injurious loading scenarios to establish cause and effect relationships to assist forensic and safetly investigations. Largely as a result of a lack of availability of paediatric clinical and Post-Mortem-Human-Surrogate (PMHS) experimental data, a new approach to infant head injury experimentation has been developed. A coupled-methodology, combining a physical infant head surrogate, producing “real world” global, regional and localised impact response data and a computational Finite-Element (FE-head) model was created and validated against available PMHS and physical model global impact response data. Experimental impact simulations were performed to investigate regional and localised injury vulnerability. Different regions of the head produced accelerations significantly greater than those calculated using the currently available method of measuring the global, whole head response. The majority of material strain was produced within the relatively elastic suture and fontanelle regions, rather than the skull bones. A subsequent parametric analysis was conducted to provide a correlation between fall height and areas of maximum-stress-response and fracture-risk-probability. The FE-head was further applied to investigating fracture risk, simulating injurious PMHS impacts and a good qualitative match was observed. The FE-head shows significant potential for the study of infant head injury and is anticipated to be a motivating tool for the improvement of head injury understanding across a range of potentially injurious head loading scenarios. |
doi_str_mv | 10.1016/j.forsciint.2019.04.034 |
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Head injury in childhood is the most common cause of death or permanent disability from injury. However, insufficient understanding exists of the response of a child’s head to injurious loading scenarios to establish cause and effect relationships to assist forensic and safetly investigations. Largely as a result of a lack of availability of paediatric clinical and Post-Mortem-Human-Surrogate (PMHS) experimental data, a new approach to infant head injury experimentation has been developed. A coupled-methodology, combining a physical infant head surrogate, producing “real world” global, regional and localised impact response data and a computational Finite-Element (FE-head) model was created and validated against available PMHS and physical model global impact response data. Experimental impact simulations were performed to investigate regional and localised injury vulnerability. Different regions of the head produced accelerations significantly greater than those calculated using the currently available method of measuring the global, whole head response. The majority of material strain was produced within the relatively elastic suture and fontanelle regions, rather than the skull bones. A subsequent parametric analysis was conducted to provide a correlation between fall height and areas of maximum-stress-response and fracture-risk-probability. The FE-head was further applied to investigating fracture risk, simulating injurious PMHS impacts and a good qualitative match was observed. The FE-head shows significant potential for the study of infant head injury and is anticipated to be a motivating tool for the improvement of head injury understanding across a range of potentially injurious head loading scenarios.</description><identifier>ISSN: 0379-0738</identifier><identifier>EISSN: 1872-6283</identifier><identifier>DOI: 10.1016/j.forsciint.2019.04.034</identifier><identifier>PMID: 31125762</identifier><language>eng</language><publisher>Ireland: Elsevier B.V</publisher><subject>3D printing ; Accidental Falls ; Age ; Autopsy ; Babies ; Biomechanical Phenomena - physiology ; Biomechanics ; Bones ; Cadaver ; Children ; Computation ; Computer applications ; Computer Simulation ; Computer-Aided Design ; Craniocerebral Trauma - physiopathology ; Elastic Modulus - physiology ; Epidemiology ; Experimentation ; Finite Element Analysis ; Finite element method ; Forensic Medicine - methods ; Forensic science ; Forensic sciences ; Head ; Head injuries ; Health risks ; Humans ; Imaging, Three-Dimensional ; Impact response ; Infant ; Infant head impact injury ; Injuries ; Iron ; Mathematical models ; Mechanical properties ; Parametric analysis ; Pediatrics ; Physiology ; Printing, Three-Dimensional ; Skull Fractures - physiopathology ; Strain ; Stress, Physiological ; Surrogate modelling ; Traumatic brain injury</subject><ispartof>Forensic science international, 2019-07, Vol.300, p.170-186</ispartof><rights>2019 Elsevier B.V.</rights><rights>Copyright © 2019 Elsevier B.V. All rights reserved.</rights><rights>2019. Elsevier B.V.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c399t-ea21d10e8b3a02f5628cecfbe75ccd4916185568366882d5e026fe8b470a9d313</citedby><cites>FETCH-LOGICAL-c399t-ea21d10e8b3a02f5628cecfbe75ccd4916185568366882d5e026fe8b470a9d313</cites><orcidid>0000-0002-6058-6029 ; 0000-0003-1213-3516 ; 0000-0001-6270-6445</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.proquest.com/docview/2232640182?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995,64385,64387,64389,72469</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31125762$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Khalid, Ghaidaa A.</creatorcontrib><creatorcontrib>Prabhu, Raj K.</creatorcontrib><creatorcontrib>Arthurs, Owen</creatorcontrib><creatorcontrib>Jones, Michael D.</creatorcontrib><title>A coupled physical-computational methodology for the investigation of short fall related infant head impact injury</title><title>Forensic science international</title><addtitle>Forensic Sci Int</addtitle><description>•Head model simulated global impact response of infant cadaver and physical model.•Regions of head produced significantly greater accelerations than global response.•Majority of strain within relatively elastic suture and fontanelle regions.•Head model, produced good qualitative match with cadaver fracture risk.•Parametric analysis correlated fall height with stress-response and fracture-risk.
Head injury in childhood is the most common cause of death or permanent disability from injury. However, insufficient understanding exists of the response of a child’s head to injurious loading scenarios to establish cause and effect relationships to assist forensic and safetly investigations. Largely as a result of a lack of availability of paediatric clinical and Post-Mortem-Human-Surrogate (PMHS) experimental data, a new approach to infant head injury experimentation has been developed. A coupled-methodology, combining a physical infant head surrogate, producing “real world” global, regional and localised impact response data and a computational Finite-Element (FE-head) model was created and validated against available PMHS and physical model global impact response data. Experimental impact simulations were performed to investigate regional and localised injury vulnerability. Different regions of the head produced accelerations significantly greater than those calculated using the currently available method of measuring the global, whole head response. The majority of material strain was produced within the relatively elastic suture and fontanelle regions, rather than the skull bones. A subsequent parametric analysis was conducted to provide a correlation between fall height and areas of maximum-stress-response and fracture-risk-probability. The FE-head was further applied to investigating fracture risk, simulating injurious PMHS impacts and a good qualitative match was observed. The FE-head shows significant potential for the study of infant head injury and is anticipated to be a motivating tool for the improvement of head injury understanding across a range of potentially injurious head loading scenarios.</description><subject>3D printing</subject><subject>Accidental Falls</subject><subject>Age</subject><subject>Autopsy</subject><subject>Babies</subject><subject>Biomechanical Phenomena - physiology</subject><subject>Biomechanics</subject><subject>Bones</subject><subject>Cadaver</subject><subject>Children</subject><subject>Computation</subject><subject>Computer applications</subject><subject>Computer Simulation</subject><subject>Computer-Aided Design</subject><subject>Craniocerebral Trauma - physiopathology</subject><subject>Elastic Modulus - physiology</subject><subject>Epidemiology</subject><subject>Experimentation</subject><subject>Finite Element Analysis</subject><subject>Finite element method</subject><subject>Forensic Medicine - methods</subject><subject>Forensic science</subject><subject>Forensic sciences</subject><subject>Head</subject><subject>Head injuries</subject><subject>Health risks</subject><subject>Humans</subject><subject>Imaging, Three-Dimensional</subject><subject>Impact response</subject><subject>Infant</subject><subject>Infant head impact injury</subject><subject>Injuries</subject><subject>Iron</subject><subject>Mathematical models</subject><subject>Mechanical properties</subject><subject>Parametric analysis</subject><subject>Pediatrics</subject><subject>Physiology</subject><subject>Printing, Three-Dimensional</subject><subject>Skull Fractures - physiopathology</subject><subject>Strain</subject><subject>Stress, Physiological</subject><subject>Surrogate modelling</subject><subject>Traumatic brain injury</subject><issn>0379-0738</issn><issn>1872-6283</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqFkU2P1SAUhonRONfRv6Akbty0HqCldHkz8SuZxI2uCZeeTmloqUAnuf9exjvOwo0rCHnOe87hIeQdg5oBkx_negwxWefWXHNgfQ1NDaJ5Rg5MdbySXInn5ACi6yvohLoir1KaAaBtuXxJrgRjvO0kP5B4pDbsm8eBbtM5OWt8ZcOy7dlkF1bj6YJ5CkPw4e5MS1OaJ6RuvceU3d0fhoaRpinETEfjPY3oTS5xbh3NmumEptyXzdhcnuY9nl-TFwVM-ObxvCY_P3_6cfO1uv3-5dvN8bayou9zhYazgQGqkzDAx7bsZNGOJ-xaa4emZ5KptpVKSKkUH1oELsdCNx2YfhBMXJMPl9wthl97mVcvLln03qwY9qQ5Fxz6FpqmoO__Qeewx7L9hZINMMUL1V0oG0NKEUe9RbeYeNYM9IMWPesnLfpBi4ZGFy2l8u1j_n5acHiq--uhAMcLgOVD7h1GXVJwtTi4iDbrIbj_NvkNxYekPA</recordid><startdate>201907</startdate><enddate>201907</enddate><creator>Khalid, Ghaidaa A.</creator><creator>Prabhu, Raj K.</creator><creator>Arthurs, Owen</creator><creator>Jones, Michael D.</creator><general>Elsevier B.V</general><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7RV</scope><scope>7U7</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-6058-6029</orcidid><orcidid>https://orcid.org/0000-0003-1213-3516</orcidid><orcidid>https://orcid.org/0000-0001-6270-6445</orcidid></search><sort><creationdate>201907</creationdate><title>A coupled physical-computational methodology for the investigation of short fall related infant head impact injury</title><author>Khalid, Ghaidaa A. ; Prabhu, Raj K. ; Arthurs, Owen ; Jones, Michael D.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c399t-ea21d10e8b3a02f5628cecfbe75ccd4916185568366882d5e026fe8b470a9d313</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>3D printing</topic><topic>Accidental Falls</topic><topic>Age</topic><topic>Autopsy</topic><topic>Babies</topic><topic>Biomechanical Phenomena - physiology</topic><topic>Biomechanics</topic><topic>Bones</topic><topic>Cadaver</topic><topic>Children</topic><topic>Computation</topic><topic>Computer applications</topic><topic>Computer Simulation</topic><topic>Computer-Aided Design</topic><topic>Craniocerebral Trauma - physiopathology</topic><topic>Elastic Modulus - physiology</topic><topic>Epidemiology</topic><topic>Experimentation</topic><topic>Finite Element Analysis</topic><topic>Finite element method</topic><topic>Forensic Medicine - methods</topic><topic>Forensic science</topic><topic>Forensic sciences</topic><topic>Head</topic><topic>Head injuries</topic><topic>Health risks</topic><topic>Humans</topic><topic>Imaging, Three-Dimensional</topic><topic>Impact response</topic><topic>Infant</topic><topic>Infant head impact injury</topic><topic>Injuries</topic><topic>Iron</topic><topic>Mathematical models</topic><topic>Mechanical properties</topic><topic>Parametric analysis</topic><topic>Pediatrics</topic><topic>Physiology</topic><topic>Printing, Three-Dimensional</topic><topic>Skull Fractures - physiopathology</topic><topic>Strain</topic><topic>Stress, Physiological</topic><topic>Surrogate modelling</topic><topic>Traumatic brain injury</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Khalid, Ghaidaa A.</creatorcontrib><creatorcontrib>Prabhu, Raj K.</creatorcontrib><creatorcontrib>Arthurs, Owen</creatorcontrib><creatorcontrib>Jones, Michael D.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>ProQuest Nursing and Allied Health Journals</collection><collection>Toxicology Abstracts</collection><collection>ProQuest Health and Medical</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>ProQuest Biological Science Journals</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Forensic science international</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Khalid, Ghaidaa A.</au><au>Prabhu, Raj K.</au><au>Arthurs, Owen</au><au>Jones, Michael D.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A coupled physical-computational methodology for the investigation of short fall related infant head impact injury</atitle><jtitle>Forensic science international</jtitle><addtitle>Forensic Sci Int</addtitle><date>2019-07</date><risdate>2019</risdate><volume>300</volume><spage>170</spage><epage>186</epage><pages>170-186</pages><issn>0379-0738</issn><eissn>1872-6283</eissn><abstract>•Head model simulated global impact response of infant cadaver and physical model.•Regions of head produced significantly greater accelerations than global response.•Majority of strain within relatively elastic suture and fontanelle regions.•Head model, produced good qualitative match with cadaver fracture risk.•Parametric analysis correlated fall height with stress-response and fracture-risk.
Head injury in childhood is the most common cause of death or permanent disability from injury. However, insufficient understanding exists of the response of a child’s head to injurious loading scenarios to establish cause and effect relationships to assist forensic and safetly investigations. Largely as a result of a lack of availability of paediatric clinical and Post-Mortem-Human-Surrogate (PMHS) experimental data, a new approach to infant head injury experimentation has been developed. A coupled-methodology, combining a physical infant head surrogate, producing “real world” global, regional and localised impact response data and a computational Finite-Element (FE-head) model was created and validated against available PMHS and physical model global impact response data. Experimental impact simulations were performed to investigate regional and localised injury vulnerability. Different regions of the head produced accelerations significantly greater than those calculated using the currently available method of measuring the global, whole head response. The majority of material strain was produced within the relatively elastic suture and fontanelle regions, rather than the skull bones. A subsequent parametric analysis was conducted to provide a correlation between fall height and areas of maximum-stress-response and fracture-risk-probability. The FE-head was further applied to investigating fracture risk, simulating injurious PMHS impacts and a good qualitative match was observed. The FE-head shows significant potential for the study of infant head injury and is anticipated to be a motivating tool for the improvement of head injury understanding across a range of potentially injurious head loading scenarios.</abstract><cop>Ireland</cop><pub>Elsevier B.V</pub><pmid>31125762</pmid><doi>10.1016/j.forsciint.2019.04.034</doi><tpages>17</tpages><orcidid>https://orcid.org/0000-0002-6058-6029</orcidid><orcidid>https://orcid.org/0000-0003-1213-3516</orcidid><orcidid>https://orcid.org/0000-0001-6270-6445</orcidid></addata></record> |
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subjects | 3D printing Accidental Falls Age Autopsy Babies Biomechanical Phenomena - physiology Biomechanics Bones Cadaver Children Computation Computer applications Computer Simulation Computer-Aided Design Craniocerebral Trauma - physiopathology Elastic Modulus - physiology Epidemiology Experimentation Finite Element Analysis Finite element method Forensic Medicine - methods Forensic science Forensic sciences Head Head injuries Health risks Humans Imaging, Three-Dimensional Impact response Infant Infant head impact injury Injuries Iron Mathematical models Mechanical properties Parametric analysis Pediatrics Physiology Printing, Three-Dimensional Skull Fractures - physiopathology Strain Stress, Physiological Surrogate modelling Traumatic brain injury |
title | A coupled physical-computational methodology for the investigation of short fall related infant head impact injury |
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