A coupled physical-computational methodology for the investigation of short fall related infant head impact injury

•Head model simulated global impact response of infant cadaver and physical model.•Regions of head produced significantly greater accelerations than global response.•Majority of strain within relatively elastic suture and fontanelle regions.•Head model, produced good qualitative match with cadaver f...

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Veröffentlicht in:Forensic science international 2019-07, Vol.300, p.170-186
Hauptverfasser: Khalid, Ghaidaa A., Prabhu, Raj K., Arthurs, Owen, Jones, Michael D.
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creator Khalid, Ghaidaa A.
Prabhu, Raj K.
Arthurs, Owen
Jones, Michael D.
description •Head model simulated global impact response of infant cadaver and physical model.•Regions of head produced significantly greater accelerations than global response.•Majority of strain within relatively elastic suture and fontanelle regions.•Head model, produced good qualitative match with cadaver fracture risk.•Parametric analysis correlated fall height with stress-response and fracture-risk. Head injury in childhood is the most common cause of death or permanent disability from injury. However, insufficient understanding exists of the response of a child’s head to injurious loading scenarios to establish cause and effect relationships to assist forensic and safetly investigations. Largely as a result of a lack of availability of paediatric clinical and Post-Mortem-Human-Surrogate (PMHS) experimental data, a new approach to infant head injury experimentation has been developed. A coupled-methodology, combining a physical infant head surrogate, producing “real world” global, regional and localised impact response data and a computational Finite-Element (FE-head) model was created and validated against available PMHS and physical model global impact response data. Experimental impact simulations were performed to investigate regional and localised injury vulnerability. Different regions of the head produced accelerations significantly greater than those calculated using the currently available method of measuring the global, whole head response. The majority of material strain was produced within the relatively elastic suture and fontanelle regions, rather than the skull bones. A subsequent parametric analysis was conducted to provide a correlation between fall height and areas of maximum-stress-response and fracture-risk-probability. The FE-head was further applied to investigating fracture risk, simulating injurious PMHS impacts and a good qualitative match was observed. The FE-head shows significant potential for the study of infant head injury and is anticipated to be a motivating tool for the improvement of head injury understanding across a range of potentially injurious head loading scenarios.
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Head injury in childhood is the most common cause of death or permanent disability from injury. However, insufficient understanding exists of the response of a child’s head to injurious loading scenarios to establish cause and effect relationships to assist forensic and safetly investigations. Largely as a result of a lack of availability of paediatric clinical and Post-Mortem-Human-Surrogate (PMHS) experimental data, a new approach to infant head injury experimentation has been developed. A coupled-methodology, combining a physical infant head surrogate, producing “real world” global, regional and localised impact response data and a computational Finite-Element (FE-head) model was created and validated against available PMHS and physical model global impact response data. Experimental impact simulations were performed to investigate regional and localised injury vulnerability. Different regions of the head produced accelerations significantly greater than those calculated using the currently available method of measuring the global, whole head response. The majority of material strain was produced within the relatively elastic suture and fontanelle regions, rather than the skull bones. A subsequent parametric analysis was conducted to provide a correlation between fall height and areas of maximum-stress-response and fracture-risk-probability. The FE-head was further applied to investigating fracture risk, simulating injurious PMHS impacts and a good qualitative match was observed. 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Head injury in childhood is the most common cause of death or permanent disability from injury. However, insufficient understanding exists of the response of a child’s head to injurious loading scenarios to establish cause and effect relationships to assist forensic and safetly investigations. Largely as a result of a lack of availability of paediatric clinical and Post-Mortem-Human-Surrogate (PMHS) experimental data, a new approach to infant head injury experimentation has been developed. A coupled-methodology, combining a physical infant head surrogate, producing “real world” global, regional and localised impact response data and a computational Finite-Element (FE-head) model was created and validated against available PMHS and physical model global impact response data. Experimental impact simulations were performed to investigate regional and localised injury vulnerability. Different regions of the head produced accelerations significantly greater than those calculated using the currently available method of measuring the global, whole head response. The majority of material strain was produced within the relatively elastic suture and fontanelle regions, rather than the skull bones. A subsequent parametric analysis was conducted to provide a correlation between fall height and areas of maximum-stress-response and fracture-risk-probability. The FE-head was further applied to investigating fracture risk, simulating injurious PMHS impacts and a good qualitative match was observed. The FE-head shows significant potential for the study of infant head injury and is anticipated to be a motivating tool for the improvement of head injury understanding across a range of potentially injurious head loading scenarios.</description><subject>3D printing</subject><subject>Accidental Falls</subject><subject>Age</subject><subject>Autopsy</subject><subject>Babies</subject><subject>Biomechanical Phenomena - physiology</subject><subject>Biomechanics</subject><subject>Bones</subject><subject>Cadaver</subject><subject>Children</subject><subject>Computation</subject><subject>Computer applications</subject><subject>Computer Simulation</subject><subject>Computer-Aided Design</subject><subject>Craniocerebral Trauma - physiopathology</subject><subject>Elastic Modulus - physiology</subject><subject>Epidemiology</subject><subject>Experimentation</subject><subject>Finite Element Analysis</subject><subject>Finite element method</subject><subject>Forensic Medicine - methods</subject><subject>Forensic science</subject><subject>Forensic sciences</subject><subject>Head</subject><subject>Head injuries</subject><subject>Health risks</subject><subject>Humans</subject><subject>Imaging, Three-Dimensional</subject><subject>Impact response</subject><subject>Infant</subject><subject>Infant head impact injury</subject><subject>Injuries</subject><subject>Iron</subject><subject>Mathematical models</subject><subject>Mechanical properties</subject><subject>Parametric analysis</subject><subject>Pediatrics</subject><subject>Physiology</subject><subject>Printing, Three-Dimensional</subject><subject>Skull Fractures - physiopathology</subject><subject>Strain</subject><subject>Stress, Physiological</subject><subject>Surrogate modelling</subject><subject>Traumatic brain injury</subject><issn>0379-0738</issn><issn>1872-6283</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqFkU2P1SAUhonRONfRv6Akbty0HqCldHkz8SuZxI2uCZeeTmloqUAnuf9exjvOwo0rCHnOe87hIeQdg5oBkx_negwxWefWXHNgfQ1NDaJ5Rg5MdbySXInn5ACi6yvohLoir1KaAaBtuXxJrgRjvO0kP5B4pDbsm8eBbtM5OWt8ZcOy7dlkF1bj6YJ5CkPw4e5MS1OaJ6RuvceU3d0fhoaRpinETEfjPY3oTS5xbh3NmumEptyXzdhcnuY9nl-TFwVM-ObxvCY_P3_6cfO1uv3-5dvN8bayou9zhYazgQGqkzDAx7bsZNGOJ-xaa4emZ5KptpVKSKkUH1oELsdCNx2YfhBMXJMPl9wthl97mVcvLln03qwY9qQ5Fxz6FpqmoO__Qeewx7L9hZINMMUL1V0oG0NKEUe9RbeYeNYM9IMWPesnLfpBi4ZGFy2l8u1j_n5acHiq--uhAMcLgOVD7h1GXVJwtTi4iDbrIbj_NvkNxYekPA</recordid><startdate>201907</startdate><enddate>201907</enddate><creator>Khalid, Ghaidaa A.</creator><creator>Prabhu, Raj K.</creator><creator>Arthurs, Owen</creator><creator>Jones, Michael D.</creator><general>Elsevier B.V</general><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7RV</scope><scope>7U7</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-6058-6029</orcidid><orcidid>https://orcid.org/0000-0003-1213-3516</orcidid><orcidid>https://orcid.org/0000-0001-6270-6445</orcidid></search><sort><creationdate>201907</creationdate><title>A coupled physical-computational methodology for the investigation of short fall related infant head impact injury</title><author>Khalid, Ghaidaa A. ; 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source MEDLINE; Access via ScienceDirect (Elsevier); ProQuest Central UK/Ireland
subjects 3D printing
Accidental Falls
Age
Autopsy
Babies
Biomechanical Phenomena - physiology
Biomechanics
Bones
Cadaver
Children
Computation
Computer applications
Computer Simulation
Computer-Aided Design
Craniocerebral Trauma - physiopathology
Elastic Modulus - physiology
Epidemiology
Experimentation
Finite Element Analysis
Finite element method
Forensic Medicine - methods
Forensic science
Forensic sciences
Head
Head injuries
Health risks
Humans
Imaging, Three-Dimensional
Impact response
Infant
Infant head impact injury
Injuries
Iron
Mathematical models
Mechanical properties
Parametric analysis
Pediatrics
Physiology
Printing, Three-Dimensional
Skull Fractures - physiopathology
Strain
Stress, Physiological
Surrogate modelling
Traumatic brain injury
title A coupled physical-computational methodology for the investigation of short fall related infant head impact injury
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