Enhancing osteoblast functions on biofilm-contaminated titanium alloy by concentration-dependent use of methylene blue-mediated antimicrobial photodynamic therapy

•A MB concentration-dependent eradication efficacy against bacteria is found.•Cell function on contaminated Ti sample is enhanced with increased MB concentration in aPDT.•The aPDT treatment with 400 μg/mL MB is a promising therapeutic modality. The concentration of methylene blue (MB) photosensitize...

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Veröffentlicht in:	Photodiagnosis and photodynamic therapy 2019-09, Vol.27, p.7-18
Hauptverfasser:	Huang, Tsun-Chin, Chen, Chun-Ju, Chen, Chun-Cheng, Ding, Shinn-Jyh
Format:	Artikel
Sprache:	eng
Schlagworte:	Aggregatibacter actinomycetemcomitans - drug effects Alloys Antimicrobial efficacy Antimicrobial photodynamic therapy Biofilms - drug effects Dental implant Dose-Response Relationship, Drug Lasers, Semiconductor Methylene Blue - administration & dosage Methylene Blue - pharmacology Osteoblasts - drug effects Osteogenic activity Peri-implantitis Peri-Implantitis - drug therapy Photochemotherapy - methods Photodynamic therapy Photosensitizing Agents - administration & dosage Photosensitizing Agents - pharmacology Streptococcus mutans - drug effects Titanium
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