Development of an Interactive Outcome Estimation Tool for Laparoscopic Roux-en-Y Gastric Bypass in Mexico Based on a Cohort of 1002 Patients
Background Laparoscopic Roux-en-Y Gastric Bypass (LRYGB) is one of the most commonly performed bariatric procedures. Considering significant differences between populations around the world, surgical outcomes may vary widely. The aim of the study was to develop an educational patient-specific intera...
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| Veröffentlicht in: | Obesity surgery 2019-09, Vol.29 (9), p.2878-2885 |
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| creator | Velázquez-Fernández, David Sánchez, Hugo Monraz, Fernando Zanela, Olivo Omar Cabra, Hermilo Arturo Pantoja, Juan Pablo Sierra, Mauricio Mosti, Maureen Herrera, Miguel F. |
| description | Background
Laparoscopic Roux-en-Y Gastric Bypass (LRYGB) is one of the most commonly performed bariatric procedures. Considering significant differences between populations around the world, surgical outcomes may vary widely. The aim of the study was to develop an educational patient-specific interactive application that may estimate the potential outcomes of LRYGB in the Mexican population.
Methods
A database with 76 different variables from 1002 patients who underwent LRYGB at two Mexican Institutions between 1992 and 2014 and had a minimum of 6-month follow-up was analyzed. Descriptive and inferential statistics, as well as a multivariate regression analysis, were performed for the primary analysis. Results were based on four statistical models obtained from the cohort outcomes. A tool was designed to provide estimates of absolute weight loss (AWL) and resolution of four major comorbidities: type 2 diabetes (T2D), high blood pressure (HBP), hypercholesterolemia, and the obstructive syndrome of sleep apnea (OSAS).
Results
There were 353 males (35.2%) and 649 females (64.8%) with a mean age of 41.9 ± 12.1 years and a mean preoperative BMI of 45.3 ± 7.9 kg/m
2
. Mean AWL at 2 years was 39.02 ± 12.7 kg. Mean accumulative percentage of resolution for T2D, HBP, and dyslipidemias at the same time period was 78%, 66.2%, and 84.7%, respectively. Based on these results, the educational tool was developed.
Conclusions
We were able to develop an interactive estimation application to provide a population-based guidance for potential outcomes of LRYGB. This might be useful not only for health professionals but also for patients interested in learning potential outcomes in specific circumstances. |
| doi_str_mv | 10.1007/s11695-019-03929-x |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2232062443</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2232062443</sourcerecordid><originalsourceid>FETCH-LOGICAL-c375t-57c5c9c8a950afd778085f027d0c588f921fd1b5356cf4976156059042b29fd13</originalsourceid><addsrcrecordid>eNp9kcFu1DAQhi0EotvCC3BAlrhwMYzHcRIf6VJKpUVFqBw4WV7HgVSJHWyn2r4DD11vt4DEgZMlzzf_PzM_IS84vOEAzdvEea0kA64YCIWK7R6RFW-gZVBh-5isQNXAWoXiiByndA2AvEZ8So4E53ukWpFf792NG8M8OZ9p6Knx9MJnF43Nw42jl0u2YXL0LOVhMnkInl6FMNI-RLoxs4kh2TAPln4Jy445z77Rc5NyLD-nt7NJiQ6efnK7wQZ6apLraFEwdB1-hHjvVxZB-rkoF__0jDzpzZjc84f3hHz9cHa1_sg2l-cX63cbZkUjM5ONlVbZ1igJpu-apoVW9oBNB1a2ba-Q9x3fSiFr21eqqbmsQaqy8RZVqYgT8vqgO8fwc3Ep62lI1o2j8S4sSSMKhBqrShT01T_odViiL9MVCmsFCnEviAfKloOk6Ho9x3KveKs56H1W-pCVLlnp-6z0rjS9fJBetpPr_rT8DqcA4gCkUvLfXfzr_R_ZO1pRnmA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2226909221</pqid></control><display><type>article</type><title>Development of an Interactive Outcome Estimation Tool for Laparoscopic Roux-en-Y Gastric Bypass in Mexico Based on a Cohort of 1002 Patients</title><source>MEDLINE</source><source>SpringerLink Journals - AutoHoldings</source><creator>Velázquez-Fernández, David ; Sánchez, Hugo ; Monraz, Fernando ; Zanela, Olivo Omar ; Cabra, Hermilo Arturo ; Pantoja, Juan Pablo ; Sierra, Mauricio ; Mosti, Maureen ; Herrera, Miguel F.</creator><creatorcontrib>Velázquez-Fernández, David ; Sánchez, Hugo ; Monraz, Fernando ; Zanela, Olivo Omar ; Cabra, Hermilo Arturo ; Pantoja, Juan Pablo ; Sierra, Mauricio ; Mosti, Maureen ; Herrera, Miguel F.</creatorcontrib><description>Background
Laparoscopic Roux-en-Y Gastric Bypass (LRYGB) is one of the most commonly performed bariatric procedures. Considering significant differences between populations around the world, surgical outcomes may vary widely. The aim of the study was to develop an educational patient-specific interactive application that may estimate the potential outcomes of LRYGB in the Mexican population.
Methods
A database with 76 different variables from 1002 patients who underwent LRYGB at two Mexican Institutions between 1992 and 2014 and had a minimum of 6-month follow-up was analyzed. Descriptive and inferential statistics, as well as a multivariate regression analysis, were performed for the primary analysis. Results were based on four statistical models obtained from the cohort outcomes. A tool was designed to provide estimates of absolute weight loss (AWL) and resolution of four major comorbidities: type 2 diabetes (T2D), high blood pressure (HBP), hypercholesterolemia, and the obstructive syndrome of sleep apnea (OSAS).
Results
There were 353 males (35.2%) and 649 females (64.8%) with a mean age of 41.9 ± 12.1 years and a mean preoperative BMI of 45.3 ± 7.9 kg/m
2
. Mean AWL at 2 years was 39.02 ± 12.7 kg. Mean accumulative percentage of resolution for T2D, HBP, and dyslipidemias at the same time period was 78%, 66.2%, and 84.7%, respectively. Based on these results, the educational tool was developed.
Conclusions
We were able to develop an interactive estimation application to provide a population-based guidance for potential outcomes of LRYGB. This might be useful not only for health professionals but also for patients interested in learning potential outcomes in specific circumstances.</description><identifier>ISSN: 0960-8923</identifier><identifier>EISSN: 1708-0428</identifier><identifier>DOI: 10.1007/s11695-019-03929-x</identifier><identifier>PMID: 31104284</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Adult ; Cohort Studies ; Diabetes Mellitus, Type 2 ; Female ; Gastric Bypass - statistics & numerical data ; Humans ; Hyperlipidemias ; Hypertension ; Laparoscopy ; Laparoscopy - statistics & numerical data ; Male ; Medicine ; Medicine & Public Health ; Mexico ; Middle Aged ; Models, Statistical ; Obesity, Morbid - surgery ; Original Contributions ; Sleep Apnea Syndromes ; Surgery ; Treatment Outcome ; Weight Loss - physiology</subject><ispartof>Obesity surgery, 2019-09, Vol.29 (9), p.2878-2885</ispartof><rights>Springer Science+Business Media, LLC, part of Springer Nature 2019</rights><rights>Obesity Surgery is a copyright of Springer, (2019). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c375t-57c5c9c8a950afd778085f027d0c588f921fd1b5356cf4976156059042b29fd13</citedby><cites>FETCH-LOGICAL-c375t-57c5c9c8a950afd778085f027d0c588f921fd1b5356cf4976156059042b29fd13</cites><orcidid>0000-0001-9187-9038</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s11695-019-03929-x$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s11695-019-03929-x$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,777,781,27905,27906,41469,42538,51300</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31104284$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Velázquez-Fernández, David</creatorcontrib><creatorcontrib>Sánchez, Hugo</creatorcontrib><creatorcontrib>Monraz, Fernando</creatorcontrib><creatorcontrib>Zanela, Olivo Omar</creatorcontrib><creatorcontrib>Cabra, Hermilo Arturo</creatorcontrib><creatorcontrib>Pantoja, Juan Pablo</creatorcontrib><creatorcontrib>Sierra, Mauricio</creatorcontrib><creatorcontrib>Mosti, Maureen</creatorcontrib><creatorcontrib>Herrera, Miguel F.</creatorcontrib><title>Development of an Interactive Outcome Estimation Tool for Laparoscopic Roux-en-Y Gastric Bypass in Mexico Based on a Cohort of 1002 Patients</title><title>Obesity surgery</title><addtitle>OBES SURG</addtitle><addtitle>Obes Surg</addtitle><description>Background
Laparoscopic Roux-en-Y Gastric Bypass (LRYGB) is one of the most commonly performed bariatric procedures. Considering significant differences between populations around the world, surgical outcomes may vary widely. The aim of the study was to develop an educational patient-specific interactive application that may estimate the potential outcomes of LRYGB in the Mexican population.
Methods
A database with 76 different variables from 1002 patients who underwent LRYGB at two Mexican Institutions between 1992 and 2014 and had a minimum of 6-month follow-up was analyzed. Descriptive and inferential statistics, as well as a multivariate regression analysis, were performed for the primary analysis. Results were based on four statistical models obtained from the cohort outcomes. A tool was designed to provide estimates of absolute weight loss (AWL) and resolution of four major comorbidities: type 2 diabetes (T2D), high blood pressure (HBP), hypercholesterolemia, and the obstructive syndrome of sleep apnea (OSAS).
Results
There were 353 males (35.2%) and 649 females (64.8%) with a mean age of 41.9 ± 12.1 years and a mean preoperative BMI of 45.3 ± 7.9 kg/m
2
. Mean AWL at 2 years was 39.02 ± 12.7 kg. Mean accumulative percentage of resolution for T2D, HBP, and dyslipidemias at the same time period was 78%, 66.2%, and 84.7%, respectively. Based on these results, the educational tool was developed.
Conclusions
We were able to develop an interactive estimation application to provide a population-based guidance for potential outcomes of LRYGB. This might be useful not only for health professionals but also for patients interested in learning potential outcomes in specific circumstances.</description><subject>Adult</subject><subject>Cohort Studies</subject><subject>Diabetes Mellitus, Type 2</subject><subject>Female</subject><subject>Gastric Bypass - statistics & numerical data</subject><subject>Humans</subject><subject>Hyperlipidemias</subject><subject>Hypertension</subject><subject>Laparoscopy</subject><subject>Laparoscopy - statistics & numerical data</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Mexico</subject><subject>Middle Aged</subject><subject>Models, Statistical</subject><subject>Obesity, Morbid - surgery</subject><subject>Original Contributions</subject><subject>Sleep Apnea Syndromes</subject><subject>Surgery</subject><subject>Treatment Outcome</subject><subject>Weight Loss - physiology</subject><issn>0960-8923</issn><issn>1708-0428</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp9kcFu1DAQhi0EotvCC3BAlrhwMYzHcRIf6VJKpUVFqBw4WV7HgVSJHWyn2r4DD11vt4DEgZMlzzf_PzM_IS84vOEAzdvEea0kA64YCIWK7R6RFW-gZVBh-5isQNXAWoXiiByndA2AvEZ8So4E53ukWpFf792NG8M8OZ9p6Knx9MJnF43Nw42jl0u2YXL0LOVhMnkInl6FMNI-RLoxs4kh2TAPln4Jy445z77Rc5NyLD-nt7NJiQ6efnK7wQZ6apLraFEwdB1-hHjvVxZB-rkoF__0jDzpzZjc84f3hHz9cHa1_sg2l-cX63cbZkUjM5ONlVbZ1igJpu-apoVW9oBNB1a2ba-Q9x3fSiFr21eqqbmsQaqy8RZVqYgT8vqgO8fwc3Ep62lI1o2j8S4sSSMKhBqrShT01T_odViiL9MVCmsFCnEviAfKloOk6Ho9x3KveKs56H1W-pCVLlnp-6z0rjS9fJBetpPr_rT8DqcA4gCkUvLfXfzr_R_ZO1pRnmA</recordid><startdate>20190901</startdate><enddate>20190901</enddate><creator>Velázquez-Fernández, David</creator><creator>Sánchez, Hugo</creator><creator>Monraz, Fernando</creator><creator>Zanela, Olivo Omar</creator><creator>Cabra, Hermilo Arturo</creator><creator>Pantoja, Juan Pablo</creator><creator>Sierra, Mauricio</creator><creator>Mosti, Maureen</creator><creator>Herrera, Miguel F.</creator><general>Springer US</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-9187-9038</orcidid></search><sort><creationdate>20190901</creationdate><title>Development of an Interactive Outcome Estimation Tool for Laparoscopic Roux-en-Y Gastric Bypass in Mexico Based on a Cohort of 1002 Patients</title><author>Velázquez-Fernández, David ; Sánchez, Hugo ; Monraz, Fernando ; Zanela, Olivo Omar ; Cabra, Hermilo Arturo ; Pantoja, Juan Pablo ; Sierra, Mauricio ; Mosti, Maureen ; Herrera, Miguel F.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c375t-57c5c9c8a950afd778085f027d0c588f921fd1b5356cf4976156059042b29fd13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Adult</topic><topic>Cohort Studies</topic><topic>Diabetes Mellitus, Type 2</topic><topic>Female</topic><topic>Gastric Bypass - statistics & numerical data</topic><topic>Humans</topic><topic>Hyperlipidemias</topic><topic>Hypertension</topic><topic>Laparoscopy</topic><topic>Laparoscopy - statistics & numerical data</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Mexico</topic><topic>Middle Aged</topic><topic>Models, Statistical</topic><topic>Obesity, Morbid - surgery</topic><topic>Original Contributions</topic><topic>Sleep Apnea Syndromes</topic><topic>Surgery</topic><topic>Treatment Outcome</topic><topic>Weight Loss - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Velázquez-Fernández, David</creatorcontrib><creatorcontrib>Sánchez, Hugo</creatorcontrib><creatorcontrib>Monraz, Fernando</creatorcontrib><creatorcontrib>Zanela, Olivo Omar</creatorcontrib><creatorcontrib>Cabra, Hermilo Arturo</creatorcontrib><creatorcontrib>Pantoja, Juan Pablo</creatorcontrib><creatorcontrib>Sierra, Mauricio</creatorcontrib><creatorcontrib>Mosti, Maureen</creatorcontrib><creatorcontrib>Herrera, Miguel F.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Obesity surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Velázquez-Fernández, David</au><au>Sánchez, Hugo</au><au>Monraz, Fernando</au><au>Zanela, Olivo Omar</au><au>Cabra, Hermilo Arturo</au><au>Pantoja, Juan Pablo</au><au>Sierra, Mauricio</au><au>Mosti, Maureen</au><au>Herrera, Miguel F.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Development of an Interactive Outcome Estimation Tool for Laparoscopic Roux-en-Y Gastric Bypass in Mexico Based on a Cohort of 1002 Patients</atitle><jtitle>Obesity surgery</jtitle><stitle>OBES SURG</stitle><addtitle>Obes Surg</addtitle><date>2019-09-01</date><risdate>2019</risdate><volume>29</volume><issue>9</issue><spage>2878</spage><epage>2885</epage><pages>2878-2885</pages><issn>0960-8923</issn><eissn>1708-0428</eissn><abstract>Background
Laparoscopic Roux-en-Y Gastric Bypass (LRYGB) is one of the most commonly performed bariatric procedures. Considering significant differences between populations around the world, surgical outcomes may vary widely. The aim of the study was to develop an educational patient-specific interactive application that may estimate the potential outcomes of LRYGB in the Mexican population.
Methods
A database with 76 different variables from 1002 patients who underwent LRYGB at two Mexican Institutions between 1992 and 2014 and had a minimum of 6-month follow-up was analyzed. Descriptive and inferential statistics, as well as a multivariate regression analysis, were performed for the primary analysis. Results were based on four statistical models obtained from the cohort outcomes. A tool was designed to provide estimates of absolute weight loss (AWL) and resolution of four major comorbidities: type 2 diabetes (T2D), high blood pressure (HBP), hypercholesterolemia, and the obstructive syndrome of sleep apnea (OSAS).
Results
There were 353 males (35.2%) and 649 females (64.8%) with a mean age of 41.9 ± 12.1 years and a mean preoperative BMI of 45.3 ± 7.9 kg/m
2
. Mean AWL at 2 years was 39.02 ± 12.7 kg. Mean accumulative percentage of resolution for T2D, HBP, and dyslipidemias at the same time period was 78%, 66.2%, and 84.7%, respectively. Based on these results, the educational tool was developed.
Conclusions
We were able to develop an interactive estimation application to provide a population-based guidance for potential outcomes of LRYGB. This might be useful not only for health professionals but also for patients interested in learning potential outcomes in specific circumstances.</abstract><cop>New York</cop><pub>Springer US</pub><pmid>31104284</pmid><doi>10.1007/s11695-019-03929-x</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0001-9187-9038</orcidid></addata></record> |
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| ispartof | Obesity surgery, 2019-09, Vol.29 (9), p.2878-2885 |
| issn | 0960-8923 1708-0428 |
| language | eng |
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| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | Adult Cohort Studies Diabetes Mellitus, Type 2 Female Gastric Bypass - statistics & numerical data Humans Hyperlipidemias Hypertension Laparoscopy Laparoscopy - statistics & numerical data Male Medicine Medicine & Public Health Mexico Middle Aged Models, Statistical Obesity, Morbid - surgery Original Contributions Sleep Apnea Syndromes Surgery Treatment Outcome Weight Loss - physiology |
| title | Development of an Interactive Outcome Estimation Tool for Laparoscopic Roux-en-Y Gastric Bypass in Mexico Based on a Cohort of 1002 Patients |
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