Leptin in the regulation of the immunometabolism of adipose tissue‐macrophages

Obesity is a pandemic disease affecting around 15% of the global population. Obesity is a major risk factor for other conditions, such as type 2 diabetes and cardiovascular diseases. The adipose tissue is the main secretor of leptin, an adipokine responsible for the regulation of food intake and ene...

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Veröffentlicht in:	Journal of leukocyte biology 2019-09, Vol.106 (3), p.703-716
Hauptverfasser:	Monteiro, Lauar, Pereira, Jéssica Aparecida da Silva, Palhinha, Lohanna, Moraes‐Vieira, Pedro Manoel M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose Tissue - cytology Animals Humans Immunity immunometabolism inflammation leptin Leptin - metabolism Macrophages - immunology Macrophages - metabolism obesity Receptors, Leptin - metabolism Signal Transduction
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