Comparative transcriptomic analysis reveals the gene expression profiles in the liver and spleen of Japanese pufferfish (Takifugu rubripes) in response to Vibrio harveyi infection

Japanese pufferfish (Takifugu rubripes) is one of the main marine aquatic fish species cultured in Asia due to its high nutritional value. In recent years, disease caused by Vibrio harveyi infections have led to serious mortality in Japanese pufferfish industry. To understand the complex molecular m...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Fish & shellfish immunology 2019-07, Vol.90, p.308-316
Hauptverfasser: Peng, Hongyu, Yang, Boxue, Li, Boyan, Cai, Zhonglu, Cui, Qianjin, Chen, Mingkang, Liu, Xia, Yang, Xu, Jiang, Chen
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 316
container_issue
container_start_page 308
container_title Fish & shellfish immunology
container_volume 90
creator Peng, Hongyu
Yang, Boxue
Li, Boyan
Cai, Zhonglu
Cui, Qianjin
Chen, Mingkang
Liu, Xia
Yang, Xu
Jiang, Chen
description Japanese pufferfish (Takifugu rubripes) is one of the main marine aquatic fish species cultured in Asia due to its high nutritional value. In recent years, disease caused by Vibrio harveyi infections have led to serious mortality in Japanese pufferfish industry. To understand the complex molecular mechanisms between V. harveyi and Japanese pufferfish, we performed a transcriptome analysis of liver and spleen samples from Japanese pufferfish at 1 and 2 day post-infection. Between-group comparisons revealed 922 genes that were significantly differentially expressed. The altered genes emphasized the function in several immune related pathways including MAPK signaling pathway, JAK-STAT signaling pathway, toll-like receptor signaling pathway, cytokine-cytokine receptor interaction and lysosomal pathway. The data generated in this study provided insight into the responses of Japanese pufferfish against V. harveyi at the transcriptome level, promoting our comprehensive understanding of immune responses for aquatic animal against V. harveyi. •Comparative transcriptome of Japanese pufferfish challenged with Vibrio harveyi were sequenced.•Between-group comparisons revealed 922 genes that were significantly differentially expressed.•Several immune related pathways were enriched.•Results will provide valuable resources for immune responses of aquatic animals against V. harveyi.
doi_str_mv 10.1016/j.fsi.2019.04.304
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2232019028</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S105046481930542X</els_id><sourcerecordid>2232019028</sourcerecordid><originalsourceid>FETCH-LOGICAL-c353t-30e3eaadc3748ba9ca3b0e32d7fd11a7d869c2f383fa20159b6a8f4b5fcb87203</originalsourceid><addsrcrecordid>eNp9UcuO1DAQjBCIXRY-gAvycTkk2HGe4oRGy0srcVm4Wo7T3vGQ2MadjJjv4gfpMAtHTrZc1dWuqix7KXghuGjeHAqLrii56AteFZJXj7JLwfs67_uqfbzda55XTdVdZM8QD5zzRjb8aXYhCek7UV5mv3ZhjjrpxR2BLUl7NMnFJczOMO31dEKHLMER9IRs2QO7Bw8MfsYEiC54FlOwbgJkzv_BJxJKNDoyjBOAZ8GyzzpqDwgsrtZCsg737PpOf3d2vV9ZWgdaCfh6kyDZGDxRl8C-OQIC2-t0hJMj1IJZaOfz7Iml78CLh_Mq-_r-5m73Mb_98uHT7t1tbmQtl1xykKD1aGRbdYPujZYDPZVja0chdDt2TW9KKztpNWVY90OjO1sNtTVD15ZcXmXXZ13y-GMFXNTs0MA0kZmwoipLuWXPy46o4kw1KSAmsComN-t0UoKrrSt1UNSV2viKV4q6oplXD_LrMMP4b-JvOUR4eyYAmTw6SAqNA29gdImSUGNw_5H_DRlGqiY</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2232019028</pqid></control><display><type>article</type><title>Comparative transcriptomic analysis reveals the gene expression profiles in the liver and spleen of Japanese pufferfish (Takifugu rubripes) in response to Vibrio harveyi infection</title><source>Access via ScienceDirect (Elsevier)</source><creator>Peng, Hongyu ; Yang, Boxue ; Li, Boyan ; Cai, Zhonglu ; Cui, Qianjin ; Chen, Mingkang ; Liu, Xia ; Yang, Xu ; Jiang, Chen</creator><creatorcontrib>Peng, Hongyu ; Yang, Boxue ; Li, Boyan ; Cai, Zhonglu ; Cui, Qianjin ; Chen, Mingkang ; Liu, Xia ; Yang, Xu ; Jiang, Chen</creatorcontrib><description>Japanese pufferfish (Takifugu rubripes) is one of the main marine aquatic fish species cultured in Asia due to its high nutritional value. In recent years, disease caused by Vibrio harveyi infections have led to serious mortality in Japanese pufferfish industry. To understand the complex molecular mechanisms between V. harveyi and Japanese pufferfish, we performed a transcriptome analysis of liver and spleen samples from Japanese pufferfish at 1 and 2 day post-infection. Between-group comparisons revealed 922 genes that were significantly differentially expressed. The altered genes emphasized the function in several immune related pathways including MAPK signaling pathway, JAK-STAT signaling pathway, toll-like receptor signaling pathway, cytokine-cytokine receptor interaction and lysosomal pathway. The data generated in this study provided insight into the responses of Japanese pufferfish against V. harveyi at the transcriptome level, promoting our comprehensive understanding of immune responses for aquatic animal against V. harveyi. •Comparative transcriptome of Japanese pufferfish challenged with Vibrio harveyi were sequenced.•Between-group comparisons revealed 922 genes that were significantly differentially expressed.•Several immune related pathways were enriched.•Results will provide valuable resources for immune responses of aquatic animals against V. harveyi.</description><identifier>ISSN: 1050-4648</identifier><identifier>EISSN: 1095-9947</identifier><identifier>DOI: 10.1016/j.fsi.2019.04.304</identifier><identifier>PMID: 31059812</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Differentially expressed genes ; Immune response ; Takifugu rubripes ; Transcriptome analysis ; Vibrio harveyi</subject><ispartof>Fish &amp; shellfish immunology, 2019-07, Vol.90, p.308-316</ispartof><rights>2019 Elsevier Ltd</rights><rights>Copyright © 2019 Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c353t-30e3eaadc3748ba9ca3b0e32d7fd11a7d869c2f383fa20159b6a8f4b5fcb87203</citedby><cites>FETCH-LOGICAL-c353t-30e3eaadc3748ba9ca3b0e32d7fd11a7d869c2f383fa20159b6a8f4b5fcb87203</cites><orcidid>0000-0003-4969-6128</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.fsi.2019.04.304$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>315,781,785,3551,27926,27927,45997</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31059812$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Peng, Hongyu</creatorcontrib><creatorcontrib>Yang, Boxue</creatorcontrib><creatorcontrib>Li, Boyan</creatorcontrib><creatorcontrib>Cai, Zhonglu</creatorcontrib><creatorcontrib>Cui, Qianjin</creatorcontrib><creatorcontrib>Chen, Mingkang</creatorcontrib><creatorcontrib>Liu, Xia</creatorcontrib><creatorcontrib>Yang, Xu</creatorcontrib><creatorcontrib>Jiang, Chen</creatorcontrib><title>Comparative transcriptomic analysis reveals the gene expression profiles in the liver and spleen of Japanese pufferfish (Takifugu rubripes) in response to Vibrio harveyi infection</title><title>Fish &amp; shellfish immunology</title><addtitle>Fish Shellfish Immunol</addtitle><description>Japanese pufferfish (Takifugu rubripes) is one of the main marine aquatic fish species cultured in Asia due to its high nutritional value. In recent years, disease caused by Vibrio harveyi infections have led to serious mortality in Japanese pufferfish industry. To understand the complex molecular mechanisms between V. harveyi and Japanese pufferfish, we performed a transcriptome analysis of liver and spleen samples from Japanese pufferfish at 1 and 2 day post-infection. Between-group comparisons revealed 922 genes that were significantly differentially expressed. The altered genes emphasized the function in several immune related pathways including MAPK signaling pathway, JAK-STAT signaling pathway, toll-like receptor signaling pathway, cytokine-cytokine receptor interaction and lysosomal pathway. The data generated in this study provided insight into the responses of Japanese pufferfish against V. harveyi at the transcriptome level, promoting our comprehensive understanding of immune responses for aquatic animal against V. harveyi. •Comparative transcriptome of Japanese pufferfish challenged with Vibrio harveyi were sequenced.•Between-group comparisons revealed 922 genes that were significantly differentially expressed.•Several immune related pathways were enriched.•Results will provide valuable resources for immune responses of aquatic animals against V. harveyi.</description><subject>Differentially expressed genes</subject><subject>Immune response</subject><subject>Takifugu rubripes</subject><subject>Transcriptome analysis</subject><subject>Vibrio harveyi</subject><issn>1050-4648</issn><issn>1095-9947</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><recordid>eNp9UcuO1DAQjBCIXRY-gAvycTkk2HGe4oRGy0srcVm4Wo7T3vGQ2MadjJjv4gfpMAtHTrZc1dWuqix7KXghuGjeHAqLrii56AteFZJXj7JLwfs67_uqfbzda55XTdVdZM8QD5zzRjb8aXYhCek7UV5mv3ZhjjrpxR2BLUl7NMnFJczOMO31dEKHLMER9IRs2QO7Bw8MfsYEiC54FlOwbgJkzv_BJxJKNDoyjBOAZ8GyzzpqDwgsrtZCsg737PpOf3d2vV9ZWgdaCfh6kyDZGDxRl8C-OQIC2-t0hJMj1IJZaOfz7Iml78CLh_Mq-_r-5m73Mb_98uHT7t1tbmQtl1xykKD1aGRbdYPujZYDPZVja0chdDt2TW9KKztpNWVY90OjO1sNtTVD15ZcXmXXZ13y-GMFXNTs0MA0kZmwoipLuWXPy46o4kw1KSAmsComN-t0UoKrrSt1UNSV2viKV4q6oplXD_LrMMP4b-JvOUR4eyYAmTw6SAqNA29gdImSUGNw_5H_DRlGqiY</recordid><startdate>20190701</startdate><enddate>20190701</enddate><creator>Peng, Hongyu</creator><creator>Yang, Boxue</creator><creator>Li, Boyan</creator><creator>Cai, Zhonglu</creator><creator>Cui, Qianjin</creator><creator>Chen, Mingkang</creator><creator>Liu, Xia</creator><creator>Yang, Xu</creator><creator>Jiang, Chen</creator><general>Elsevier Ltd</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-4969-6128</orcidid></search><sort><creationdate>20190701</creationdate><title>Comparative transcriptomic analysis reveals the gene expression profiles in the liver and spleen of Japanese pufferfish (Takifugu rubripes) in response to Vibrio harveyi infection</title><author>Peng, Hongyu ; Yang, Boxue ; Li, Boyan ; Cai, Zhonglu ; Cui, Qianjin ; Chen, Mingkang ; Liu, Xia ; Yang, Xu ; Jiang, Chen</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c353t-30e3eaadc3748ba9ca3b0e32d7fd11a7d869c2f383fa20159b6a8f4b5fcb87203</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Differentially expressed genes</topic><topic>Immune response</topic><topic>Takifugu rubripes</topic><topic>Transcriptome analysis</topic><topic>Vibrio harveyi</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Peng, Hongyu</creatorcontrib><creatorcontrib>Yang, Boxue</creatorcontrib><creatorcontrib>Li, Boyan</creatorcontrib><creatorcontrib>Cai, Zhonglu</creatorcontrib><creatorcontrib>Cui, Qianjin</creatorcontrib><creatorcontrib>Chen, Mingkang</creatorcontrib><creatorcontrib>Liu, Xia</creatorcontrib><creatorcontrib>Yang, Xu</creatorcontrib><creatorcontrib>Jiang, Chen</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Fish &amp; shellfish immunology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Peng, Hongyu</au><au>Yang, Boxue</au><au>Li, Boyan</au><au>Cai, Zhonglu</au><au>Cui, Qianjin</au><au>Chen, Mingkang</au><au>Liu, Xia</au><au>Yang, Xu</au><au>Jiang, Chen</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comparative transcriptomic analysis reveals the gene expression profiles in the liver and spleen of Japanese pufferfish (Takifugu rubripes) in response to Vibrio harveyi infection</atitle><jtitle>Fish &amp; shellfish immunology</jtitle><addtitle>Fish Shellfish Immunol</addtitle><date>2019-07-01</date><risdate>2019</risdate><volume>90</volume><spage>308</spage><epage>316</epage><pages>308-316</pages><issn>1050-4648</issn><eissn>1095-9947</eissn><abstract>Japanese pufferfish (Takifugu rubripes) is one of the main marine aquatic fish species cultured in Asia due to its high nutritional value. In recent years, disease caused by Vibrio harveyi infections have led to serious mortality in Japanese pufferfish industry. To understand the complex molecular mechanisms between V. harveyi and Japanese pufferfish, we performed a transcriptome analysis of liver and spleen samples from Japanese pufferfish at 1 and 2 day post-infection. Between-group comparisons revealed 922 genes that were significantly differentially expressed. The altered genes emphasized the function in several immune related pathways including MAPK signaling pathway, JAK-STAT signaling pathway, toll-like receptor signaling pathway, cytokine-cytokine receptor interaction and lysosomal pathway. The data generated in this study provided insight into the responses of Japanese pufferfish against V. harveyi at the transcriptome level, promoting our comprehensive understanding of immune responses for aquatic animal against V. harveyi. •Comparative transcriptome of Japanese pufferfish challenged with Vibrio harveyi were sequenced.•Between-group comparisons revealed 922 genes that were significantly differentially expressed.•Several immune related pathways were enriched.•Results will provide valuable resources for immune responses of aquatic animals against V. harveyi.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>31059812</pmid><doi>10.1016/j.fsi.2019.04.304</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0003-4969-6128</orcidid></addata></record>
fulltext fulltext
identifier ISSN: 1050-4648
ispartof Fish & shellfish immunology, 2019-07, Vol.90, p.308-316
issn 1050-4648
1095-9947
language eng
recordid cdi_proquest_miscellaneous_2232019028
source Access via ScienceDirect (Elsevier)
subjects Differentially expressed genes
Immune response
Takifugu rubripes
Transcriptome analysis
Vibrio harveyi
title Comparative transcriptomic analysis reveals the gene expression profiles in the liver and spleen of Japanese pufferfish (Takifugu rubripes) in response to Vibrio harveyi infection
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-17T18%3A17%3A14IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Comparative%20transcriptomic%20analysis%20reveals%20the%20gene%20expression%20profiles%20in%20the%20liver%20and%20spleen%20of%20Japanese%20pufferfish%20(Takifugu%20rubripes)%20in%20response%20to%20Vibrio%20harveyi%20infection&rft.jtitle=Fish%20&%20shellfish%20immunology&rft.au=Peng,%20Hongyu&rft.date=2019-07-01&rft.volume=90&rft.spage=308&rft.epage=316&rft.pages=308-316&rft.issn=1050-4648&rft.eissn=1095-9947&rft_id=info:doi/10.1016/j.fsi.2019.04.304&rft_dat=%3Cproquest_cross%3E2232019028%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2232019028&rft_id=info:pmid/31059812&rft_els_id=S105046481930542X&rfr_iscdi=true