Enhanced efficiency of mitochondria-targeted peptide SS-31 for acute kidney injury by pH-responsive and AKI-kidney targeted nanopolyplexes

Oxidative stress is an important pathological mechanism for acute kidney injury (AKI). SS-31, as a mitochondria-targeted peptide with strong antioxidant activity, is a good candidate for the treatment of AKI. However, an efficient treatment of AKI requires frequent administration of SS-31, which is...

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Veröffentlicht in:	Biomaterials 2019-08, Vol.211, p.57-67
Hauptverfasser:	Liu, Di, Jin, Feiyang, Shu, Gaofeng, Xu, Xiaoling, Qi, Jing, Kang, Xuqi, Yu, Hui, Lu, Kongjun, Jiang, Saiping, Han, Feng, You, Jian, Du, Yongzhong, Ji, Jiansong
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute kidney injury AKI-kidney targeted Nanoparticles pH-responsive SS-31
Online-Zugang:	Volltext
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