Clinical significance of tumor miR-21, miR-221, miR-143, and miR-106a as biomarkers in patients with osteosarcoma

Objective: To investigate the expression of miR-21, miR-221, miR-143, and miR-106a in patients’ osteosarcoma samples, and to explore the correlation between these microRNAs (miRNAs) and the clinical stage of osteosarcoma. Methods: RNA was extracted from tumor and tumor-adjacent normal bone tissues f...

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Veröffentlicht in:	The International journal of biological markers 2019-06, Vol.34 (2), p.184-193
Hauptverfasser:	Zhao, Hui, Yan, Peng, Wang, Jian, Zhang, Yuqiang, Zhang, Mingchao, Wang, Zaijun, Fu, Qiang, Liang, Weiguo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Biomarkers Biomarkers, Tumor - genetics Bone cancer Bone Neoplasms - genetics Bone Neoplasms - pathology Case-Control Studies Clinical significance Female Follow-Up Studies Gene Expression Regulation, Neoplastic Humans Lung cancer Male Metastases Metastasis MicroRNAs MicroRNAs - genetics Middle Aged miRNA Osteosarcoma Osteosarcoma - genetics Osteosarcoma - pathology Polymerase chain reaction Prognosis Reverse transcription Sarcoma Therapeutic applications Young Adult
Online-Zugang:	Volltext
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