Signals trigger state-specific transcriptional programs to support diversity and homeostasis in immune cells

Macrophages play key roles in the immune systems of humans and other mammals. Here, we performed single-cell analyses of the mRNAs and proteins of human macrophages to compare their responses to the signaling molecules lipopolysaccharide (LPS), a component of Gram-negative bacteria, and palmitate (P...

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Veröffentlicht in:Science signaling 2019-05, Vol.12 (581)
Hauptverfasser: Fischer, Cornelius, Metsger, Maria, Bauch, Sophia, Vidal, Ramon, Böttcher, Michael, Grote, Phillip, Kliem, Magdalena, Sauer, Sascha
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Sprache:eng
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