Combination of ions promotes cell migration via extracellular signal‑regulated kinase 1/2 signaling pathway in human gingival fibroblasts

Wound healing is a dynamic process that involves highly coordinated cellular events, including proliferation and migration. Oral gingival fibroblasts serve a central role in maintaining oral mucosa homeostasis, and their functions include the coordination of physiological tissue repair. Recently, su...

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Veröffentlicht in:	Molecular medicine reports 2019-06, Vol.19 (6), p.5039-5045
Hauptverfasser:	Yamaguchi-Ueda, Kimiko, Akazawa, Yuki, Kawarabayashi, Keita, Sugimoto, Asuna, Nakagawa, Hiroshi, Miyazaki, Aya, Kurogoushi, Rika, Iwata, Kokoro, Kitamura, Takamasa, Yamada, Aya, Hasegawa, Tomokazu, Fukumoto, Satoshi, Iwamoto, Tsutomu
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergies Aluminum Aluminum - chemistry Aprotinin Biocompatibility Biomedical materials Boron Boron - chemistry Cell adhesion & migration Cell culture Cell growth Cell Line Cell migration Cell Movement Cell Proliferation - drug effects Composite materials Dental caries Extracellular signal-regulated kinase Fibroblasts Fibroblasts - cytology Fibroblasts - metabolism Gingiva Gingiva - cytology Homeostasis Humans Ions Ions - chemistry Ions - pharmacology Kinases MEK inhibitors Metals Mitogen-Activated Protein Kinase 1 - metabolism Mitogen-Activated Protein Kinase 3 - metabolism Mucosa p38 Mitogen-Activated Protein Kinases - metabolism Phosphorylation Phosphorylation - drug effects Signal transduction Signal Transduction - drug effects Silicon Silicon - chemistry Sodium Sodium - chemistry Strontium Strontium - chemistry Wound care Wound healing Wounds
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